MicroautophagyProteasomeProteasome storage granule (PSG)Proteasomes are highly abundant protein complexes that are responsible for most regulated protein degradation in cells under favorable growth conditions. When yeast cells are under nutritional stress, most proteasomes exit the nucleus and either ...
小自噬, 2、微型细胞自噬 (microautophagy),又称为小自噬, ,又称为小自噬 是指通过溶酶体膜的内陷、突起和/或分隔, …wenku.baidu.com|基于3个网页 3. 微小细胞自噬 ...型式的细胞自噬,牵涉到细胞内膜动态性的没入及重组:微小细胞自噬(microautophagy)及巨大细胞自噬(macroautophagy)。research.ncku.edu.tw|...
根据底物进入溶酶体内的途径不同可将自噬分为3 种类型: 微自噬( microautophagy)、巨自噬( macroautophagy)和分子伴侣介导的自噬(chaperone mediated autophagy,CMA)。巨自噬即通常所指的自噬, 胞质被来源于内质网的非核糖体区域、高尔基体等脱落的双层膜所包绕。
Autophagy is a self-catabolic process through which cellular components are delivered to lysosomes for degradation. There are three types of autophagy, i.e., macroautophagy, chaperone-mediated autophagy (CMA), and microautophagy. In macroautophagy, a portion of the cytoplasm is wrapped by the auto...
In this report we present evidence that distinct autophagic mechanisms control cytosolic protein delivery to late endosomes and identify a microautophagy-like process that delivers soluble cytosolic proteins to the vesicles of late endosomes/multivesicular bodies (MVBs). This microautophagy-like process ...
Microautophagy is a non-selective lysosomal degradation process that was first identified in 1966 and has been studied mainly in yeast. It involves direct phagocytosis of cytoplasmic cargo by autophagic tubules at the plasma membrane that mediate both invagination and lysis of vesicles into...
Microautophagy, the non-selective lysosomal degradative process, involves direct engulfment of cytoplasmic cargo at a boundary membrane by autophagic tubes, which mediate both invagination and vesicle scission into the lumen. With its constitutive characteristics, microautophagy of soluble substrates can be...
(2016) Selective endosomal microautophagy is starvation-inducible in Drosophila. Autophagy 12, 1984-1999Mukherjee, A.; Patel, B.; Koga, H.; Cuervo, A.M.; Jenny, A. Selective endosomal microautophagy is starvation-inducible in Drosophila. Autophagy 2016, 12, 1984-1999. [CrossRef] [PubMed]...
This microautophagy-like degradation pathway described by Sahu et al. (2011) does not depend on the canonical autophagic machinery, as a knockdown of the ubiquitin E1 enzyme homolog Atg7, required for LC3 and Atg12 activa- tion, did not affect the delivery of the ...
21and microautophagy (direct encapsulation of cytosolic substrates into lysosomal lumen)22. Mechanism and biological consequences of macroautophagy and CMA have been extensively investigated, whereas those of microautophagy remain unclear, in particular, in mammalian cells23. In this Article, we examine ...