Dromedary camel CD14high MHCIIhigh monocytes display inflammatory properties and are reduced in newborn camel calvesMonocyte subsetsDromedary camelFlow cytometryPhagocytosisAdhesion moleculesGating strategy of camel monocyte subsets. Camel leukocytes were separated by hypotonic lysis of erythrocytes and separated...
Using data from nearly 400 GCs, we determined that EBVaGCs display high mRNA levels for virtually all MHC-II genes, as well as the MHC-II-like α- and β-chains, and the invariant chain encoded by CD74 (Figs.1,2,3,5). We concurrently detected high levels of CIITA and RFX5 expressi...
that specifically targets SEB by single-cell sequencing using PBMCs isolated from volunteers enrolled in a phase I clinical trial of the five-antigenS. aureusvaccine. X-ray crystallography studies revealed that Hm0487 exhibits high affinity for a linear B cell epitope in SEB (SEB138-147), which...
MHC II immunogenicity specifically lowered variant frequencies in tumors under high immune pressure, particularly with high TCR clonality and MHC II expression. A similar trend was shown for MHC I neoepitopes, but only in particular tissue types. In summary, we report immune selection imposed by ...
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry. 仅用于科研。不用于诊断过程。未经明确授权不得转售。
Functional recombinant MHC class Ⅱ molecules and high-throughput peptide-binding assays 作者:Sune ...
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry. 仅用于科研。不用于诊断过程。未经明确授权不得转售。
根据 Padi4 的表达,作者将巨噬细胞分为两组:Padi4 高表达细胞(Padi4high)和 Padi4 低表达细胞(Padi4low)。作者发现,与 Padi4 高表达的巨噬细胞相比,Padi4 低表达的巨噬细胞中直接编码 MHC II 类的基因(如 H2-Aa、H2-Ab1 和 Ciita)以及编码参与 MHC II 类机制转录调控的辅助因子的基因的表达水平更高...
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HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry. 仅用于科研。不用于诊断过程。未经明确授权不得转售。