A. (2004). Assembly of major histocompatibility complex (MHC) class II transcription factors: association and promoter recognition of RFX proteins. Biochemistry 43, 12750 -12760.Burd AL, Ingraham RH, Goldrick SE, Kroe RR, Crute JJ, Grygon CA. Assembly of major histocompatability complex (...
MHC class II protein complex bindingMHC class II receptor activitypeptide antigen bindingmajor histocompatibility complex protein 参与通路 peptide antigen assembly with MHC class II protein complexantigen processing and presentation of peptide or polysaccharide antigen via MHC class IIpolysaccharide ...
Presents evidence that suggests a role for transmembrane domain interactions in the assembly of class II major histocompatibility complex (MHC) molecules. Proteins resulting from mutations in the transmembrane domains of the class II MHC alpha or beta chains; Interactions mediated by a structural motif...
MHC class II is unclear. Other tumors secrete inhibitory cytokines like IL-10 to suppress MHC class II and other responses, which is particularly clear for melanomas (Dummeret al., 1996) and EBV-induced B cell tumors (Benjaminet al., 1992). TheEBVgenome encodes a homologous protein for ...
Major histocompatibility complex (MHC) molecules, also designated human leukocyte antigen (HLA) molecules, are cell-surface receptors that bind foreign peptides and present them to T lymphocytes. MHC class I molecules consist of two polypeptide chains, an α or heavy chain and β-2-Microglobulin,...
protein complex assembly intracellular protein transport defense response signal transduction cell proliferation immunoglobulin mediated immune response antigen processing and presentation of endogenous antigen antigen processing and presentation of exogenous peptide antigen via MHC class II positive regulation of B...
Molecular Chaperones in MHC Class I and Class II Biosynthesis and AssemblyMHC class I and class II molecules are multisubunit receptors that require correct assembly of their individual subunits prior to cell surface expression. MHC class I molecules are comprised of a polymorphic transmembrane heavy ...
SANTACRUZBIOTECHNOLOGY,INC.ThePowertoQuestionMHCclassII(15G4):sc-53946SantaCruzBiotechnology,Inc.1.800.457.3801831.457.3800fax831.457.3801Europe+008004573800049622145030.scbtBACKGROUNDMajorhistocompatibilitycomplex(MHC)molecules,alsodesignatedhumanleukocyteantigen(HLA)molecules,arecell-surfacereceptorsthatbindforeignpeptide...
et al. Mice lacking the MHC class II-associated invariant chain. Cell 72, 635–648 (1993). Article CAS PubMed Google Scholar Bikoff, E. K. et al. Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking ...
The localization and intracellular transport of major histocompatibility complex (MHC) class II molecules nd lysosomal hydrolases were studied in I-Cell Disease (ICD) B lymphoblasts, which possess a mannose 6-phosphate (Man-6-P)-independent targeting pathway for lysosomal enzymes. In the trans-Golgi...