MHC class II molecules are found on A.Only Interferon -gamma activated cellsB.B cells, dendritic cells and macrophagesC.Virtually all cells in the bodyD.Virtually all nucleated cells in the body的答案是什么.用刷刷题APP,拍照搜索答疑.刷刷题
MHC class II molecules are expressed by the professional antigen-presenting cells (APCs) of the immune system. APCs use MHC class II molecules to provide CD4-positive T cells with an overview of the surrounding tissue environment. These interactions are important for activating T cells during infec...
We have produced mice that lack major histocompatibility complex class II antigens, permitting us to evaluate the role of these molecules in diverse aspects of T and B cell differentiation. The mutant mice show near-complete elimination of CD4+ T lymphocytes from the spleen and lymph nodes; the...
MHC class II molecules expressed on the surface of specialized antigen presenting cells (APCs)2 function by presenting peptides derived from foreign protein antigens to specific CD4 T cells, a process that initiates and propagates immune responses (1). The interaction of MHC-II-peptide complexes ...
MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II...
CD4 interacts with non-polymorphic residues of MHC class II. H2-Ab1 heterodimer chains alpha (DQA) and beta (DQB) are both anchored in the membrane. H2-Ab1 plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are...
HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides. Nature 360, 474–477 (1992). Article ADS CAS PubMed Google Scholar Denzin, L. K. & Cresswell, P. HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates...
However, the Hp proteins that bind to class II MHC and trigger apoptosis are not known. Since urease is a major Hp product that stimulates cytokine secretion by class II MHC+ cells, we hypothesized that apoptosis in gastric epithelial cells is signaled through class II MHC molecules subsequent ...
More than 90% of the major histocompatibility complex (MHC) class II molecules on antigenpresenting cells (APC) have in their binding site a peptide derive... Mouritsen,S.,Dalum,... - 《Immunology》 被引量: 9发表: 1994年 The role of MHC class II in immune responses in cattle. molecul...
MHC class I molecules are ubiquitously expressed while MHC class II molecules are expressed in specialized Antigen Presenting Cells (APCs) like dendritic cells, B cells and macrophages and in several cell types under inflamed conditions. Therefore, it is unlikely that MHC class I is expressed by ...