MHC class Ⅱ molecules are found on ( ) A. Virtually all cells in the body B. B cells, DC and Mφ C. Virtually all nucleated cells in the body D. Only on virally-infected cells. 相关知识点: 试题来源: 解析 B 反馈 收藏
Major histocompatibility complex (MHC) molecules, also designated human leukocyte antigen (HLA) molecules, are cell-surface receptors that bind foreign peptides and present them to T lymphocytes. MHC class I molecules consist of two polypeptide chains, an 伪 or heavy chain and 尾-2-Microglobulin,...
MHC class II molecules are expressed by the professional antigen-presenting cells (APCs) of the immune system. APCs use MHC class II molecules to provide CD4-positive T cells with an overview of the surrounding tissue environment. These interactions are important for activating T cells during infec...
dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ...
class II molecules are synthesized with their peptide-binding site blocked by invariant chain (Ii), and they aquire the capacity to bind antigens only after Ii has been degraded in the compartments where peptides reside. MHC class II molecules present exogenously derived antigen to CD4+ T lympho...
MHC class II molecules are found on A.Only Interferon -gamma activated cellsB.B cells, dendritic cells and macrophagesC.Virtually all cells in the bodyD.Virtually all nucleated cells in the body的答案是什么.用刷刷题APP,拍照搜索答疑.刷刷题
MHC class II molecules can present “tumor-specific antigens” like Epstein Barr viral (EBV) antigen EBNA-1 (Vooet al., 2002) and melanoma-specific antigens like tyrosinase andgp 100(Parkhurstet al., 2003; Topalianet al., 1994). Still, although class II presentation is occurring, an eff...
MHC class II molecules expressed on the surface of specialized antigen presenting cells (APCs)2 function by presenting peptides derived from foreign protein antigens to specific CD4 T cells, a process that initiates and propagates immune responses (1). The interaction of MHC-II-peptide complexes ...
MHC-class-II-positive T cells are found in tissues involved in autoimmune disorders. Stimulation of class II molecules by monoclonal antibodies (mAbs) or bacterial superantigens induces protein tyrosine phosphorylation through activation of protein tyrosine kinases in T cells, and class II signals modu...
dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 ...