Viruses and bacteria are known to subvert the immune system using mimic or inhibitory proteins. Here the authors show that the protein Ank5 from the bacterium Orientia tsutsugamushi inhibits nuclear translocation and promotes proteasomal degradation of the MHC class I gene transactivator NLRC5. Haley ...
MHC Class I, (H-2K) Mouse Antibody, FITC ANT-267 500µg ($275) 1mg ($440) ($0) Shipped at Room temp. Add to Cart Catalogue number ANT-267 Type Mouse Antibody Monoclonal. Introduction MHC Class I is a membrane spanning molecule consisting of 2 proteins. MHC Class I is just about...
Proteins of the major histocompatibility complex class I (MHCI) are known for their role in the vertebrate adaptive immune response, and are required for normal postnatal brain development and plasticity. However, it remains unknown if MHCI proteins are present in the mammalian brain before birth. ...
The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes. Eur. J. Immunol. 28:3423.Fanger NA, Cosman D, Peterson L, Braddy SC, Maliszewski CR, Borges L: The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediat...
MHC Class I, (H-2K) Mouse Antibody 英文名称: MHC Class I, (H-2K) Mouse Antibody 总访问: 274 国产/进口: 进口 半年访问: 20 产地/品牌: prospec 产品类别: 抗体 规格: ANT-176 最后更新: 2024-12-5 货号: CAS 号: 参考报价: 询价 立即询价 电话咨询 ...
Major histocompatibility complex (MHC) class I chain-related protein A (MICA) and MHC class I chain-related protein B (MICB) are polymorphic proteins that are induced upon stress, damage or transformation of cells which act as a ‘kill me’ signal through the natural-killer group 2, member...
Pillars Article: Normal Development of Mice Deficient in β2M, MHC Class I Proteins, and CD8+ T Cells. Science. 248: 1227–1230 Beverly H. Koller,Philippa Marrack,John W. Kappler,... - 《Journal of Immunology:official Journal of the American Association of Immunologists》 被引量: 22发表:...
Major histocompatibility complex molecules are proteins involved in the adaptive immune response. There are two main classes of MHC molecules: class I and class II. Each has a different distribution in the body and plays a slightly different role....
As was suggested by the missing self hypothesis, MHC class I molecules play a major role in NK cell inhibition. However, as stated above, in some cases, even the loss of MHC class I proteins is not enough to render the cells susceptible for NK cell attack. The most remarkable example is...
HLA (human leucocyte antigen)-A2 is an MHC Class I protein with primary functions in T-cell development and initi-ation of immune cell responses. MHC I proteins also play roles in intercellular adhesion, apoptosis, cell proliferation and neuronal plasticity. By utilizing a sequence comparison analy...