The MHC class I binding proteins leukocyte immunoglobulin-like receptor (LIR)-1 and -2 recognize a similar broad spectrum of HLA-A, -B and -C alleles but are differentially expressed in lymphocytes, monocytes, and dendritic cells. In monocytes, phosphorylation of LIR-1 and LIR-2 ...
Proteins of the major histocompatibility complex class I (MHCI) are known for their role in the vertebrate adaptive immune response, and are required for normal postnatal brain development and plasticity. However, it remains unknown if MHCI proteins are present in the mammalian brain before birth. ...
Major histocompatibility complex (MHC) class I chain-related protein A (MICA) and MHC class I chain-related protein B (MICB) are polymorphic proteins that are induced upon stress, damage or transformation of cells which act as a ‘kill me’ signal through the natural-killer group 2, member...
These constitutively expressed proteins are assembled on the SXY module of the MHC class I promoter as a multiprotein/DNA complex termed enhanceosome [23–25]. NLRC5 binds to this multiprotein complex to form the CITA enhanceosome (see Box 1 for further details) and in turn transactivates ...
MHC Class I, (H-2K) Mouse Antibody 英文名称: MHC Class I, (H-2K) Mouse Antibody 总访问: 274 国产/进口: 进口 半年访问: 20 产地/品牌: prospec 产品类别: 抗体 规格: ANT-176 最后更新: 2024-12-5 货号: CAS 号: 参考报价: 询价 立即询价 电话咨询 ...
Pillars Article: Normal Development of Mice Deficient in β2M, MHC Class I Proteins, and CD8+ T Cells. Science. 248: 1227–1230 Beverly H. Koller,Philippa Marrack,John W. Kappler,... - 《Journal of Immunology:official Journal of the American Association of Immunologists》 被引量: 22发表:...
HLA (human leucocyte antigen)-A2 is an MHC Class I protein with primary functions in T-cell development and initi-ation of immune cell responses. MHC I proteins also play roles in intercellular adhesion, apoptosis, cell proliferation and neuronal plasticity. By utilizing a sequence comparison analy...
Background:The MHC class I chain-related (MIC) proteins are related to the Major histocompatibility complex (MHC) class I proteins which are ubiquitously expressed and mediate the recognition of intracellular antigens by cytotoxic T cells. The MHC class I chain-related (MIC) proteins are recognize...
Proteins of the major histocompatibility complex class I (MHC I), predominantly known for antigen presentation in the immune system, have recently been shown to be necessary for developmental neural refinement and adult synaptic plasticity. However, their roles in nonneuronal cell populations in the ...
MHC class I proteins mediate functions in anti-pathogen defense. MHC diversity has already been investigated by many studies in model avian species, but here we chose the bar-headed goose, a worldwide migrant bird, as a non-model avian species. Sequences from exons encoding the peptide-binding...