Several techniques have been employed for the detection and characterization of ctDNA within the total pool of cell-free DNA (cfDNA), one of which is the modified Fast Aneuploidy Screening Test-Sequencing System (mFAST-SeqS). This affordable and robust assay enables the quantitation of a sample...
Fast/sensitive protein sequence similarity search. Slightly slower than mmseqs2, much more sensitive. - TravisWheelerLab/mmoreseqs
mFAST-SeqS was performed using plasma of blood in which CTCs (CellSearch) were enumerated. The resulting aneuploidy score was correlated with categorized CTC count and associated with outcome. The aneuploidy score was significantly correlated with CTC count, but discordance was observed in 31.6% when...
mFast‐SeqS‐based aneuploidy score in circulating cell‐free DNA is a prognostic biomarker in prostate cancerdoi:10.1002/1878-0261.13449Isebia, Khrystany T.Mostert, BiancaDeger, TeomanKraan, Jacode Weerd, VanjaOomen‐de Hoop, EstherHamberg, Paul...