美[meθɪ'leɪʃ(ə)n] 英[meθɪ'leɪʃ(ə)n] n.甲基化作用 网络甲基化酌;甲基化反应;甲基化药物 英汉 网络释义 n. 1. 甲基化作用 例句 释义: 全部,甲基化作用,甲基化酌,甲基化反应,甲基化药物 更多例句筛选
Aberrant DNA methylation in the promoter regions of gene, which leads to inactivation of tumor suppressor and other cancer-related genes in cancer cells, is the most well-defined epigenetic hallmark in gastric cancer. The advantages of gene methylation as a target for detection and diagnosis of ...
transcriptional regulation of T1R1 gene. Subsequently, high DNA methylation decreased expression of T1R1 in intestinal tract. It could be a new mechanism to explain, at least partially, the vegetarian adaptation of grass carp by regulation of expression of umami receptor via epigenetic modification. ...
DNA methylation can inhibit gene expression by altering chromatin structure. Therefore, the correct occurrence and ongoing maintenance of the DNA methylation state is of great significance for biological processes such as embryonic development, genetic imprinting, and X chromosome inactivation.26 In a ...
Genetically driven DNAm is associated with gene expression of co-localizing genes Each EstiMeth model corresponds to a CpG that is likely to be under strong genetic control. Given the role of DNAm in the regulation of gene expression8, we investigated the relationship between EstiMeth CpGs and...
functional transcripts of IBM1. ASI1 also associates with AIPP2, which has a PHD domain, AIPP3, which has a BAH domain, and the POL II carboxy-terminal domain phosphatase CARBOXY-TERMINAL PHOSPHATASELIKE 2135. Intriguingly, mutations in the three proteins had opposing effects on gene regulation...
Composition biases of 450K and EPIC arrays Consider the scenario where we have performed differential methylation analysis on individual CpG sites. In order to perform gene set enrichment analysis based on the results from a probe-wise differential methylation analysis, we need to annotate each probe...
Methylation-specific PCR (MS-qPCR) - an amplification technique used for studying gene or sequence-specific DNA methylation. DNA methylationis an epigenetic mechanism involving the addition of a methyl group to the 5 position of cytosine in DNA. This process can turn genes on or off and can be...
RNAmethylation, anepigenetic modificationthat does not alter gene sequence, may be important to diversebiological processes. Protein regulators ofRNA methylationinclude “writers,”“erasers,” and “readers,” which respectively deposit, remove, and recognize methylated RNA. RNA methylation, particularly ...
1. An isolated nucleic acid molecule comprising a gene located on Arabidopsis thaliana chromosome 5, lower arm, said gene occupying a segment of said chromosome 5, lower arm, flanked on the centromeric side within 20 kilobases by a gene encoding a zinc-finger protein and on the telomeric side...