Arti Singh PHD, in Current Research in Pharmacology and Drug Discovery, 2021 4.3 Methotrexate Methotrexate is an anti-metabolite in the anthracycline class of drugs which is mainly used in the treatment of breast cancer, lung cancer, bladder cancer, leukemia, and osteosarcoma (Gottlieb et al., ...
First-line therapy in combination with mercaptopurine for maintenance of drug-induced remissions of acute lymphoblastic leukemia (ALL).Has been used in high doses as a component of some alternative combination chemotherapy regimens for remission induction in ALL, but not generally considered a drug of...
Drug class: antimetabolites Breastfeeding Patient resources Methotrexate Injection (Subcutaneous) patient information Methotrexate Oral Solution Other brands Otrexup, Trexall, Rasuvo, Rheumatrex Dose Pack, ... +3 more Professional resources Methotrexate monograph Methotrexate Injection (FDA) Methotrexate Sodiu...
If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or ...
Methotrexate is a member of the antimetabolite drug class. Drugs in this classification, including methotrexate, azathioprine, mycophenolate mofetil, and leflunomide, exert anti-inflammatory activity...doi:10.1007/978-3-540-75387-2_28Eric Barton Suhler...
摘要: Methotrexate is a member of the antimetabolite drug class. Drugs in this classification, including methotrexate, azathioprine, mycophenolate mofetil, and leflunomide, exert anti-inflammatory activity...DOI: 10.1007/978-3-540-75387-2_28 年份: 2016 ...
The antifolate methotrexate is a widely used drug for the treatment of various malignant tumors. Enzyme and fluorescence-based immunoassay tests are used to analyze methotrexate concentrations, but are known for their cross reactivity to the inactive metabolite 2,4-Diamino-N10methylpteroic acid (DAMPA...
Ther. Class. antineoplastics antirheumatics (DMARDs) immunosuppressants Pharm. Class. antimetabolites There's more to see -- the rest of this topic is available only to subscribers. Citation Vallerand, April Hazard., et al. "Methotrexate." Davis's Drug Guide, 19th ed., F.A. Davis Company...
Methotrexate (MTX, Rheumatrex), an antifolate drug used in cancer treatment, has also been used in the disease management of RA since the 1950s. Because of its quicker therapeutic onset among all DMARDs and its demonstrated efficacy, tolerability, and low cost, MTX has been the firstline ...
Harmful buildup warning: Certain health problems can make your body clear this drug more slowly. This can cause the drug to build up in your body and raise your risk of side effects. If this occurs, your doctor may decrease your dose or stop your treatment. Before starting this drug, tel...