be used as an antigen, a nucleic acid capable of producing the viral vector, a cell having the vector or the nucleic acid capable of producing the vector introduced therein or a lysate of the cell to a non-human animal and collecting the antibody or antibody-producing cell from the animal...
In some embodiments, the invention relates to methods for creating a monoclonal antibody that specifically binds to antigen. The method may start from a polyclonal population of antibodies such as a non-specific polyclonal population or a polyclonal population of antibodies that specifically bind to ...
The application of human monoclonal antibodies to medical ... S Shirahata,Y Katakura,K Teruya - 《Methods in Cell Biology》 被引量: 84发表: 1998年 Cathepsin L-specific monoclonal antibodies, hybridomas for producing the same and a method of using the same It is possible to specifically ...
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Preclinical development of monoclonal antibodies: Considerations for the use of non-human primates The development of mAbs remains high on the therapeutic agenda for the majority of pharmaceutical and biotechnology companies. Often, the only relevant spe... K Chapman,N Pullen,L Coney,... - 《Mabs...
The hybridomas are formed by fusing splenocytes from immunized BALB/c mice with SP2/0-Ag 14 myeloma cells. Monoclonal and monospecific, polyclonal antibodies to these cytoplasmic antigens find application in the im- munodiagnosis of Candida infections. 展开 ...
et al. (1994) Monoclonal antibodies prepared against the DNA polymerase from Thermus aquaticus are potent inhibitors of enzyme activity. J. Immunol. Methods 172, 147–63. Schaefer, B.C. (1995) Revolutions in rapid amplification of cDNA ends: New strategies for polymerase chain reaction cloning ...
(2) the integrative analysis of molecules to characterize cell types and their functions regarding pathophysiological processes based on molecular signatures. Here, we summarize the technologies for single-cell multiomics analyses (mRNA-genome, mRNA-DNA methylation, mRNA-chromatin accessibility, and mRNA-...
OBTAINING THE MONOCLONAL ANTIBODIES AND THE DEVELOPMENT OF MEANS AND METHODS OF THE DIFFERENTIAL DIAGNOSTICS OF THE TRANSMISSIVE GASTROENTERITIS OF PIGS AN... OM Strizhakova 被引量: 0发表: 1996年 A TOUCH PAD AND A METHOD OF OPERATING THE TOUCH PAD A touch pad is controlled to detect a ...
3.A method according to claim 2 wherein an assay is performed to identify a unit container which is positive for the presence of cells producing antibodies having affinity equal to or greater than 1012liter mol−1to an antigen of interest. ...