Metformin-associated vitamin B12 deficiency is a well-established side effect, especially in patients taking higher doses of metformin or who have existing risk factors. Severe deficiency causes a wide range of systemic disorders. Gait instability, which leads to frequent falling, is ...
The majority of the women had not had their B12levels measured. However, upon testing, almost 1 in 10 were found to have a B12deficiency. Although metformin is recommended for the first-line treatment of type 2 diabetes, it is associated with vitamin B12deficiency, which itself increases the ...
After six months of rehabilitation, he could walk independently with a stick but there was persistent lower-limb ataxia and sensory deficits (with residual high T2 signal). This patient had multiple risk factors for developing B12 deficiency: vegetarianism, age, diabetes mellitus and Metformin use....
For one, metformin is known to interfere with the absorption of B12, and a vitamin B12 deficiency can cause a variety of symptoms, such as fatigue, headaches, and depression. Additionally, the deficiency can also increase the risk of anemia. As such, individuals using metformin should regularly...
CLINICAL AND BIOCHEMIICAL MANIFESTATIONS OF VITAMIN B12 DEFICIENCY IN TYPE 2 DIABETIC PATIENTS TREATED WITH METFORMIN- A COMPARATIVE STUDY Objectives: The objective of this study was to estimate the occurrence of Vitamin B12 deficiency in patients with type 2 diabetes mellitus treated with metformin, ...
Our companion article outlines how metformin use can lead to a clinically significant deficiency in vitamin B12, and describes the problems this can cause. In this comment, we outline a project conducted in four primary care practices that aimed to improve metformin-relat...
Metformin: Vitamin B12 deficiency and peripheral neuropathy: case report
Metformin and vitamin B12 deficiency Comment on Tidsskr Nor Laegeforen. 2007 Jan 4;127(1):65. JS Scozzari - 《Archives of Internal Medicine》 被引量: 89发表: 2002年 Miglitol, an α-glucosidase inhibitor, prevents the metformin-induced fall in serum folate and vitamin B12 in subjects with ...
In the study, 14 (18.6%) had B12 deficiency and 17 (22.3%) were in the low normal range. There was no correlation between the duration of Metformin use and the vitamin B12 level. Likewise there was no correlation observed in the MCV level and vitamin B12 deficiency sta...
Vitamin B12 deficiency is an easily preventable side effect of metformin therapy. It is essential to determine the prevalence of this condition in order to prevent the occurrence of complications, such as peripheral neuropathy and ... O Marar,S Senturk,A Agha,... 被引量: 12发表: 2011年 Per...