Breast cancerBrain metastasisEpidemiologySurvivalCáncer de mamaMetástasis cerebralEpidemiologíaSupervivenciaIntroduction Breast carcinoma is the most common malignancy in women worldwide. It is also one of the most frequent causes of brain metastasis (BM). Studies have identified BM as one of the worst...
To address this shortcoming, the researchers used clinical breast cancer specimens from the Breast Cancer Campaign Tissue Bank and preclinical laboratory modeling. Ultimately, the researchers found that “β1-mediated process outgrowth in BCa cells required the presence and activity of fyn kinas...
In subject area: Pharmacology, Toxicology and Pharmaceutical Science This is also called metastatic breast cancer, where cancer spreads to multiple organs of the body such as the brain, bones, lungs, and liver, etc. From: Targeted Nanomedicine for Breast Cancer Therapy, 2022 ...
Metastatic breast cancer to the brain: gene expression analysis with in vivo and in vitro blockage of local factors that can interfere with colonization an... LMD Silva 被引量: 0发表: 2009年 Mutually exclusive expression of DLX2 and DLX5/6 is associated with the metastatic potential of the ...
Metastatic Breast Cancer at a Glance: Scenarios of BC Brain- and BC Bone-Metastasis by IllustrationsThe machinery of metastasis is supposed to be the final effort of cancer cells' programming, but requires to be clearly defined. However, it is the success of cancer cells' journey from the ...
Vijayakrishna Gadi, MD, PhD, presents the case of a 54-year-old woman with HER2-positive metastatic breast cancer exhibiting bone, liver, and brain lesions, and key opinion leaders share their perspectives on the most appropriate treatment approaches tai
When breast cancer becomes advanced and spreads to other organs, patient survival is drastically reduced, prompting the need to explore the genes that may cause tumor cells to metastasize.
The identification of brain metastatic breast cancer (BMBC) mechanisms responsible for brain metastasis is imperative to develop new therapies. The relevance of heparanase (HPSE) in cancer invasion and metastasis has been establishe. Heparanase is the only known functional endoglycosidase in mammals and...
Here we observe a striking and unexpected pattern of CTC generation dynamics in both patients with breast cancer and mouse models, highlighting that most spontaneous CTC intravasation events occur during sleep. Further, we demonstrate that rest-phase CTCs are highly prone to metastasize, whereas ...
Ifbreast cancerspreads to yourlungs, it can make you feel: Short of breath Tired When it spreads to yourliver, it can cause: Belly pain or swelling Appetite loss Yellowskinoreyes Tiredness Confusion If it’s in yourbrain, you might notice: ...