Bile acids are biosynthesized from cholesterol in the liver. Cholic acid (CA), chenodeoxycholic acid (CDCA), and deoxycholic acid (DCA) are major bile acids in humans. Neutral (classical) pathway is the major pathway of the bile acid biosynthesis in adult humans, which starts from 7蓱-...
Metabolism of Bile Acids Bile acids are biosynthesized from cholesterol in the liver. Cholic acid (CA), chenodeoxycholic acid (CDCA), and deoxycholic acid (DCA) are major bile acid... H Takikawa - Springer Japan 被引量: 0发表: 2017年 The role of colon anaerobes in the metabolism of bile...
Metabolism of Bile Acids. I. Absorption, Distribution, Excretion, and Metabolism of Ursodeoxycholic Acid Metabolism of Bile Acids. I. Absorption, Distribution, Excretion, and Metabolism of Ursodeoxycholic AcidThe fate after oral or intravenous administration of ... TAKAHIKO,HOSHITA,MAMI,... - 《...
参考文献 Wahlström A, Sayin S I , Marschall H U , et al. Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism. Cell Metabolism, 2016, 24(1):41-50. Q. de Aguiar Vallim T , Tarling E , Edwards P . Pleiotropic Roles of Bile Acids in Metabolism. ...
Bile acids (BAs) are amphipathic steroid acids whose production and diversity depend on both host and microbial metabolism. These metabolites have emerged as biologically active signalling molecules that inform organs of nutrient availability. Their acti
Of all the novel glucoregulatory molecules discovered in the past 20 years, bile acids (BAs) are notable for the fact that they were hiding in plain sight. BAs were well known for their requirement in dietary lipid absorption and biliary cholesterol secretion, due to their micelle-forming prope...
Certain bile acid oxazoline derivatives (100 μM), but not corresponding unconjugated bile acids (100 μM), were found to inhibit the growth of Eubacterium sp. V.P.I. 12708. The growth inhibition was correlated with the polarity of the steroid portion of the bile acid oxazoline. Primary cu...
Iso-bile acids, the 3β-hydroxy epimers of the normally occurring bile acids, are commonly found in the feces of man and other animals but are not present in the bile. Since isochenodeoxycholic acid and isoursodeoxycholic acid were recently isolated from the feces of patients treated with cheno...
Enzymatic oxidation of cholesterol generates numerous distinct bile acids that function both as detergents that facilitate digestion and absorption of dietary lipids, and as hormones that activate four distinct receptors. Activation of these receptors alters gene expression in multiple tissues, leading to ...
Little information is available on the metabolism of primary and secondary bile acids during fetal life (2). There is evidence that human fetal liver can conjugate primary bile acids (2). Due to lack of microflora there is no formation of secondary bile acids (2). The occurence of ...