Unlike other cells in the body, immune cells have to be able to enter and adapt to life within diverse tissues. Immune cells develop within dedicated immune system organs, such as the bone marrow, thymus and lymphoid tissues, but also inhabit other tissu
B. Intermediary metabolism of the lung. Env. Health Perspect. 55, 149–158 (1984). Article CAS Google Scholar Mitsuishi, Y. et al. Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming. Cancer Cell 22, 66–79 (2012). Article CAS PubMed Google Scholar G...
Moreover, transcription factor analysis showed that a large number of DEGs were mainly involved with the WRKY, bHLH, and MYB transcription factor families. Determination of total soluble sugar and flavonoid contents demonstrated that important metabolic pathways and candidate genes are associated with ...
The need to produce ATP to provide energy for cellular function is, of course, essential in both quiescent and activated cells. Glucose can be used to fuel this process through two integrated pathways. The first of these, glycolysis, involves the conversion of glucose to pyruvate in the cytopla...
Filamentous fungi have the capacity to produce a battery of natural products of often unknown function, synthesized by complex metabolic pathways. Unfortun... SE Unkles - Applied Molecular Genetics of Filamentous Fungi 被引量: 195发表: 1992年 ...
We further quantitatively mapped the protein isoforms of glucose uptake signaling pathways, key metabolic pathways, and muscle specific transcription factors. Although we choose to present quantitation of these selected proteins and pathways because of their central role in muscle function, our approach ...
Metabolic control of cell death A dual role for the anti-apoptotic Bcl-2 protein in cancer: Mitochondria versus endoplasmic reticulum Hypothalamic AMPK: a canonical regulator of whole-body energy balance Regulation Mechanisms and Signaling Pathways of Autophagy. Apoptosis, autophagy & endoplasmic ret...
Comparative analysis of wild‐type and cAMP‐deathless S49 lymphoma cells identifies genes and pathways of cAMP/PKA‐promoted apoptosis The second messenger cAMP acts via protein kinase A (PKA) to induce apoptosis by mechanisms that are poorly understood. Here, we assessed a role for mitochondria ...
of plausible non-natural pathways leading to DHB that take advantage of synthetic biology approaches. We herein present a new synthetic DHB pathway whose chemical logic was inspired by the biosynthesis of homoserine. This amino acid is naturally produced by the successive action of aspartate kinase ...
Metabolic engineering is the use of genetic engineering to modify the metabolism of an organism. It can involve the optimization of existing biochemical pathways or the introduction of pathway components, most commonly in bacteria, yeast or plants, with the goal of high-yield production of specific...