The present invention relates to a novel glycoprotein-A repetitions predominant protein (GARP) surface marker for mesenchymal stem cells, specifically activated mesenchymal stem cells, and to a method for the isolation and/or identification of mesenchymal stem cells based on the detection of the ...
MSC therapy has been used for repairing both the structure and function of injured bone and cartilage tissues [158,313]. In addition to differentiation capacity to the different cell types, MSCs obtained from various sources have diverse capabilities of secreting many different cytokines, growth facto...
SurfaceMarkerMoleculesofHumanMesenchymalStemCell 系统标签: 干细胞分子标记mesenchymalstemmarker 组织工程与重建外科杂志2013年8月第9卷第4期 ·综述· doi:10.3969/j.issn.1673-0364.2013.04.015 干细胞根据所处的发育阶段可分为胚胎干细胞和成体 干细胞,间充质干细胞(MSC)是体干细胞家族的重要 员,是一类中胚层来...
The present invention provides a mesenchymal stem cell expressing at least one cell surface marker selected from the group consisting of CD201, CD46, CD56, CD147, and CD165. This mesenchymal stem cell expressing the abovementioned specific marker is positive for CD29, CD73, CD90, CD105 and...
Although direct depletion of TAMSCs is difficult in the TME, because they express a limited set of cell surface markers, upstream and downstream modulators of TAMSCs during tumorigenesis and development have been gradually clarified, and it is possible to cure tumours by targeting these ...
(HSC), MSCs, andfibrocytes. BM-MSCs are the best characterized mesoderm-derived stromal cells with multipotent differentiation capacity. These cells express neither hematopoietic nor endothelialcell surface markers, but display fibroblast-like morphology, extensive proliferation capacity and clonal expansion,...
markers\\{MSCs\\}pluripotencystromal cellsBackground aims Mesenchymal stromal/stem cells (MSCs) can be isolated from human bone marrow (BM), expanded ex聽vivo and identified via numerous surface antigens. Despite the importance of these cells in regenerative therapy programs, it is unclear whether...
Notably, MSC-EVs express EV surface markers CD63, CD9 and CD81, as well as mesenchymal stem cell surface markers CD44, CD73, and CD90 [78]. In addition, proteins contained in the extracellular vesicles secreted by MSCs are a specific protein subclass that determines their unique biological ...
(Fig.1). STRO-1 and CD146 may serve as reliable surface markers for dental stem cells (DSCs). Due to their easy access, excellent propagation capacity in vitro and potent immunoregulatory properties, DSCs have been used in some preclinical studies and clinical trials for treating hyper...
cell to the site of inflammation. This is in accordance with the findings of Pedutoet al.38. They suggested that gp38+ “lymphoid” stromal cells could consist of different stromal cell subsets or maturation stages based on genes and markers profile. They identified a CXCL13 expressing gp38+...