The characterization of different types of stem cells is based primarily on the identification of molecular markers, mainly membrane, which define them. Thus, mesenchymal stem cells (MSCs) are characterized by the absence of hematopoietic antigens on their surface as CD14, CD34, and CD45, and ...
Membrane proteinsProteomicsMass spectrometryRegenerative medicineSingle cell proteomicsCell therapyStem cells and their derivatives are novel pharmaceutics that have the potential for use as tissue replacement therapies. However, the heterogeneous characteristics of stem cell cultures have hindered their biomedical...
Some membrane markers of the T- or B-cell lineage can be analyzed on sections of formalin-fixed tissue, due to the recent development of antibodies that react to formalin-denatured antigens. An alternative stain in routine histology of lymphoid organs is the Giemsa stain, which provides a ...
Neural Stem Cell Kidney Cells Advance your research into the renal corpuscle and tubule. These interactive resources will show you our reagents and assays for the identification and functional study of kidney cell types and the glomerular basement membrane (GBM). See All Kidney Cells Cells of ...
Scientists at The University of Nottingham are investigating whether stem cell markers could have a role to play in speeding up wound healing in patients suffering from inflammatory bowel disease (IBD).
Surface markers considered to be specific for human thymus-derived (T) or bone-marrow-derived (B) cells have provided new insights into the pathogenesis of several lymphoid malignancies. This study as well as that of leukaemia-associated membrane antigens will probably enable hematologists to achiev...
of CSC properties is still an open question. We find that phenotypic heterogeneity based on cell membrane markers in GBM is a dynamic process of reversible state transitions. All GBM subpopulations displayed stem cell properties and were tumorigenic, supporting the notion that cancer cells are highly...
While stem cells are best defined functionally, a number of molecular markers have been used to characterize various stem cell populations. Although functions have yet to be ascertained for many of these early markers, their unique expression pattern and timing provide a useful tool for scientists ...
Mannino et al. provide a quantitative and ultrastructural timeline of nucleophagy in yeast with lattice light sheet microscopy and correlative light and electron tomography. They identify a role for dynamin-like protein 1 in outer nuclear membrane fission. ...
“classically activated macrophages” (M1, pro-inflammatory) and “alternatively activated macrophages” (M2, anti-inflammatory). M1 and M2 macrophages can be produced following stimulation by different factors. They express different molecular markers and produce their own characteristic secretory factors,...