Dancing on damaged chromatin: functions of ATM and the RAD50/MRE11/NBS1 complex in cellular responses to DNA damage. In order to preserve and protect genetic information, eukaryotic cells have developed a signaling or communications network to help the cell respond to DNA... Kenta,Iijima,Maki,...
Characteristics of Mesenchymal Stem Cells Derived from Amniotic Membrane: A Potential Candidate for Stem Cell-Based TherapyNowadays, mesenchymal stem cells (MSCs) have elevated the hopes of patients excruciated with incurable and/or disabling diseases. Amniotic membrane-derived mesenchymal stem cells (AMS...
Centre for Cell EngineeringNature MaterialsMcMurray RJ, Gadegaard N, Tsimbouri PM, Burgess KV, McNamara LE, Tare R, Murawski K, King- ham E, Oreffo ROC, Dalby MJ. Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency. Nat Mater 2011, 10: ...
All cell lines closely resemble the original tumors with respect to phenotype, markers and detectable genetic changes. Cell morphology and marker expression is highly variable, ranging from fully polarized cells correctly expressing all basolateral epithelial markers, to cells with mesenchymal ...