C8 and C9 both bind CD59 through their pore-forming membrane attack complex perforin (MACPF) domains9,11. The pore-forming machinery of complement proteins is encoded within a structurally conserved domain shared by other immune pores12 as well as bacterial virulence factors from the cholesterol-de...
【名词解释】膜攻击复合物(membrane attack complex,MAC) 相关知识点: 试题来源: 解析 膜攻击复合物:是三条激活途径的共同末端通路.由附着于细胞膜表面的C5b6~9复合物组成。可在胞膜上形成小孔,使得小的可溶性分子、离子以及水分子自由透过胞膜,最终导致胞内渗透压降低,细胞溶解。反馈 收藏 ...
An important effector function of the human complement system is to directly kill Gram-negative bacteria via Membrane Attack Complex (MAC) pores. MAC pores are assembled when surface-bound convertase enzymes convert C5 into C5b, which together with C6, C7, C8 and multiple copies of C9 forms a...
百度试题 题目[名词解释] MAC(membrane attack complex) 相关知识点: 试题来源: 解析 即膜攻击复合物,由补体系统的C5b～C9组成。该复合物牢固附着于靶细胞表面,最终造成细胞溶解死亡。反馈 收藏
mac (redirected fromMembrane attack complex) Thesaurus Medical Financial Acronyms Encyclopedia Mac (măk) n.Slang Used as a form of address for a man whose name is unknown. [FromMac-,a common prefix in Scottish and Irish surnames.]
The "killer molecule" of complement is the membrane attack complex (MAC). It constitutes a supramolecular organization that is composed of approximately 20 protein molecules and has a molecular weight of about 1.7 million. The complex has five precursors, C5, C6, C7, C8, and C9, which are ...
百度试题 结果1 题目膜攻击复合物(membrane attack complex,MAC) 相关知识点: 试题来源: 解析 56℃ 30min 反馈 收藏
The membrane attack complex (MAC), frequently referred to as the complement membrane attack complex, is one of the methods used by theimmune systemto attack threats to the body. It is closely related to thecomplement system, which exists to aidantibodiesand other aspects of the immune system ...
Membrane Attack ComplexReference work entry pp 906 Cite this reference work entry Encyclopedic Dictionary of Polymers Jan W. Gooch A set of proteins in the complement system that lyses invading bacteria by producing lesions in their cell membranes....
Clusterin and S-protein bind to the membrane attack complex of complement (MAC) rendering it cytolytically inactive. Tissue necrosis as produced by pulsed tunable dye laser therapy (PTDL), and immune complex-related diseases such as lupus erythematosus, are accompanied by local accumulation of MAC...