【答案】:即膜攻击复合物,由补体系统的C5b~C9组成。该复合物牢固附着于靶细胞表面,最终造成细胞溶解死亡。
【名词解释】膜攻击复合物(membrane attack complex,MAC) 相关知识点: 试题来源: 解析 膜攻击复合物:是三条激活途径的共同末端通路.由附着于细胞膜表面的C5b6~9复合物组成。可在胞膜上形成小孔,使得小的可溶性分子、离子以及水分子自由透过胞膜,最终导致胞内渗透压降低,细胞溶解。反馈 收藏 ...
Biochemistry Components of the Membrane Attack Complex (MAC) of Human Complement| Functional Studies of their MACPF Domains UNIVERSITY OF SOUTH CAROLINA James M. Sodetz Damour HinsonMegan SpainThe human complement system is part of the innate immune response that acts toeliminate pathogenic organisms....
aliquots of leukoreduced RBC units, stored for 1-6weeks, for the levels of C3a, C5a, Bb, iC3b, C4d and C5b-9 [membrane attack complex (MAC)] by enzyme-linked immunosorbent assay (ELISA).We observed that only MAC levels significantly increased in RBC units as a function of storage ...
mac (redirected fromMembrane attack complex) Thesaurus Medical Financial Acronyms Encyclopedia Mac (măk) n.Slang Used as a form of address for a man whose name is unknown. [FromMac-,a common prefix in Scottish and Irish surnames.]
百度试题 结果1 题目膜攻击复合物(membrane attack complex,MAC) 相关知识点: 试题来源: 解析 56℃ 30min 反馈 收藏
An important effector function of the human complement system is to directly kill Gram-negative bacteria via Membrane Attack Complex (MAC) pores. MAC pores are assembled when surface-bound convertase enzymes convert C5 into C5b, which together with C6, C7, C8 and multiple copies of C9 forms a...
Activation of this pathway leads to formation of a multi-protein complex, called the membrane-attack complex (MAC), which forms ~100-Å wide pores in membranes leading to lysis of the targeted cells. Our goal is to understand the mechanism of MAC formation and membrane perforation by the ...
membrane attack complex 美 英 un.次膜复合物 网络膜攻击复合物 英汉 网络释义 un. 1. 次膜复合物 例句
The membrane attack complex (MAC) is one of the immune system’s first responders. Complement proteins assemble on target membranes to form pores that lyse pathogens and impact tissue homeostasis of self-cells. How MAC disrupts the membrane barrier remains unclear. Here we use electron cryo-micros...