trans-synaptic-regulatory-mechanism网络跨突触调节机制 网络释义 1. 跨突触调节机制 什么意思... ... state's regulatory mechanism 国家调节机制 trans-synaptic regulatory mechanism 跨突触调节机制 ... dict.youdao.com|基于1 个网页© 2024 Microsoft 隐私声明和 Cookie 法律声明 广告 帮助 反馈...
ELFN1 is expressed selectively in rods where it is targeted to the axonal terminals by the synaptic release machinery. At the synapse, ELFN1 binds in trans to mGluR6, the postsynaptic receptor on rod ON-bipolar cells. Elimination of ELFN1 in mice prevents the formation of synaptic contacts ...
The properties of exosomes are also beginning to entice the biomedical community since they represent potentially novel avenues for the targeted delivery of customized exosome cargo, such as miRNAs, during disease. Our findings implicating exosomes in trans-synaptic communication emerged from the ...
C., Synaptic Transmission in a Model for Stochastic Neural Activity, J. Theor. Biol., 1979, vol. 77, no. 1, pp. 65–81. Article MathSciNet Google Scholar Izhikevich, E. M., Simple Model of Spiking Neurons, IEEE Trans. Neural Netw., 2003, vol. 14, no. 6, pp. 1569–1572. ...
The effects of prolyl hydroxylase inhibition during and post, hypoxia, oxygen glucose deprivation and oxidative stress, in isolated rat hippocampal slices Ischemia reperfusion injuryOxidative stressSynaptic transmissionRoxadustatJNJ42041935PHDIs reduce cell death in hippocampal slices following an hypoxic or ...
NMDA receptors have, however, been shown to be involved in long-term potentiation (LTP) in the hippocampus6–11, a form of synaptic plasticity12 which may be involved in learning and memory11. NMDA receptors have also been found to contribute to epileptiform activity in this region13,14. We...
The role of vesicular transport proteins in synaptic transmission and neural degeneration. Classical neurotransmitters are synthesized in the cytoplasm, so they require transport into secretory vesicles for regulated exocytotic release. Previous ... Y Liu,RH Edwards - 《Annual Review of Neuroscience》 被...
[8] investigated the effect of Anle138b on amyloid-β channels for rescuing AD disease phenotypes in an amyloid mouse model, showing that it blocks these conducting channels in neuronal membranes, which could be linked to restoration of synaptic plasticity and memory function in vivo. Dominguez-...
Transmembrane transport was involved primarily in proteins for the transport of some specific substances, such as transporter for inorganic ions, sugar, synaptic vesicular amine and protein [18]“Protein processing in endoplasmic reticulum” is a significant posttranslational proteins modification, which is...
Excitatory amino acid transporters (EAATs) of the solute carrier family 1A (SLC1A) take up the neurotransmitter L-glutamate from the synaptic environment, which is necessary to keep the extracellular concentration low and prevent neurotoxicity1,2. EAATs couple uptake of one amino acid substrate mol...