Cellular mechanism of insulin resistance: potential links with inflammation. Int J Obes Relat Metab Disord. 2003;27Supl 3:6-11.Perseghin G, Petersen K, Shulman GI. Cellular mechanism of insulin resistance: potential links with inflammation. Int J Obes Relat Metab Disord 27, Suppl 3: S6 -S11...
In this study, we attempted to identify the mechanism by which miR-27 was regulated in the context of insulin resistance, a predisposed metabolic disorder... YJ Chen,LY Chueh,SY Lee,... - 《Cellular Signalling》 被引量: 0发表: 2021年 Mechanism of insulin resistance in sepsis Sepsis, a ...
NIH 1996R01 GM Mechanism of Insulin Resistance After TraumaTurinsky, Jiri / Albany Medical College NIH 1995R01 GM Mechanism of Insulin Resistance After TraumaTurinsky, Jiri / Albany Medical College NIH 1994R01 GM Mechanism of Insulin Resistance After TraumaTurinsky, Jiri / Albany Medical Colle...
Insulin resistance is a pivotal feature in the pathogenesis of type 2 diabetes, and it may be detected 10-20?y before the clinical onset of hyperglycemia. Insulin resistance is due to the reduced ability of peripheral target tissues to respond properly to insulin stimulation. In particular, impai...
Insulin resistant (KL) mice, which tolerate 300–500 units of insulin without going into convulsions, inactivate insulin in vivo and in vitro at the same rate as control (BUB) mice which convulse after 50 units of insulin. The fasting blood sugar, glucose tolerance and pancreatic insulin conten...
Retroviral protease inhibitors used as therapy for HIV-1 infection have been causally associated with serious metabolic side effects, including peripheral lipodystrophy, hyperlipidemia, insulin resistance, and in some cases, overt type 2 diabetes. The etiology of this characteristic clinical syndrome remains...
The mechanism by which the specific β-adrenoceptor agonist AJ-9677 relieves insulin resistance in vivo was investigated by studying its effects in the white and brown adipose tissues of the KK-A~y/Ta diabetic obese mouse model. AJ-9677 reduced the total weight of white adipose tissues by redu...
Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease Insulin resistance is associated with nonalcoholic fatty liver disease (NAFLD) and is a major factor in the pathogenesis of type 2 diabetes. The developmen... N Kumashiro,DM Erion,D Zhang,... - 《Proc Natl Acad Sci ...
The mechanisms responsible for the decreased high density lipoprotein (HDL) cholesterol levels associated with obesity and insulin resistance are not well ... R.,P.,F.,... - 《European Journal of Clinical Investigation》 被引量: 464发表: 1994年 Production of insulin resistance by hyperinsulinaem...
Objective To investigate the reversal effect and molecular mechanisms of NF-κB inhibitor parthenolide( PTL) on insulin resistance( IR). Methods Hep G2 cells were treated with insulin at different concentrations and time points,the glucose consumption of Hep G2 cells was measured via glucose oxidase...