Understanding these key cellular mechanisms of insulin resistandoi:10.1038/sj.ijo.0802491Perseghin, GPetersen, KShulman, G IInternational Journal of ObesityPerseghin G, Petersen K, Shulman GI. Cellular mechanism of insulin resistance: potential links with inflammation. Int J Obes Relat Metab Disord....
Mechanisms of Compensatory β-Cell Growth in Insulin-Resistant Rats. The physiological mechanisms underlying the compensatory growth of β-cell mass in insulin-resistant states are poorly understood. Using the insulin-resist... Jetton,Thomas,L.,... - 《Diabetes》 被引量: 370发表: 2005年 Insulin...
by means of x-ray photoelectron spectroscopy that an onium salt used as a photo-acid generator is deficient at the surface of the prebaked resist film... T Kumada,Y Tanaka,A Ueyama,... - Proceedings of SPIE - The International Society for Optical Engineering 被引量: 27发表: 1993年 Grape...
Dysfunction of the pancreatic β cell is an important defect in the pathogenesis of type 2 diabetes, although its exact relationship to the insulin resist... Rohit N Kulkarni §,Jens C Brüning § ∣∣,JN Winnay,... - 《Cell》 被引量: 3088发表: 1999年 Stimulation of the insulin secretor...
DNA sensing is a pivotal component of the innate immune system that is responsible for detecting mislocalized DNA and triggering downstream inflammatory pathways. Among the DNA sensors, cyclic GMP-AMP synthase (cGAS) is a primary player in detecting cyto
Mitochondria and their components have a risk of causing uncontrolled inflammation while activating innate immune responses to resist infection. First, mitochondria supply an effective platform for the NLR family pyrin domain containing 3 (NLRP3) inflammasome activation: MAVS and cardiolipin on the OMM ...
(such as cell cycle arrest, DNA repair, senescence, apoptosis, and ferroptosis), thereby helping cells/organisms to resist stimuli. p53 can also function without depending on its transcriptional activity [67]. p53 primarily functions as a transcriptional regulator, activating or suppressing the ...
sinensis treatment of RIRI. Figure 4 Thirty-eight core targets of C. sinensis for RIRI. (a) Thirty-eight core targets between C. sinensis resist RIRI with degree ≥ median, and the larger and the closer to the blue nodes represent the larger degree value. (b) Top 20 protein targets ...
Antimicrobial peptides (AMPs) have sparked significant interest as potential anti-cancer agents, thereby becoming a focal point in pursuing novel cancer-fighting strategies. These peptides possess distinctive properties, underscoring the importance of de
(such as cell cycle arrest, DNA repair, senescence, apoptosis, and ferroptosis), thereby helping cells/organisms to resist stimuli. p53 can also function without depending on its transcriptional activity [67]. p53 primarily functions as a transcriptional regulator, activating or suppressing the ...