mechanism of drug action 药物作用机制 drug action 药效 mechanism of action 作用机理 action mechanism phr. 作用机理 principle of drug action 药物作用原理 in action adv.在活动,在运转 be in action 在活动在运转在战斗 action on vt.对的作用 drug store 药房,杂货店 wonder drug 特效药 ...
美 英 un.药物作用机制 例句
Mechanism of action describes the process by which a molecule, such as a drug, functions to produce a pharmacological effect. A drug’s mechanism of action may refer to its effects on a biological readout such as cell growth, or its interaction and modulation of its direct biomolecular target...
UFT: mechanism of drug action. 来自 Semantic Scholar 喜欢 0 阅读量: 5 作者: F Cabanillas 摘要: This article details both the contribution of the purine nucleoside analogs to the current management of relapsed indolent non-Hodgkin's lymphoma (NHL) and the role of pentostatin (Nipent) in that...
drug action mechanism, BDDCS as alternative to BCSstimulus–response and ADME behaviorpharmacodynamic phase, drug–receptor interactionsreceptors, enzymes, and molecular mechanicsdrug-likeness and bioavailability challengeSummary This chapter contains sections titled: Pharmacodynamic Phase: Drug–Receptor ...
Here, we integrated 199,219 drug sensitivity measurements for 397 unique anti‐cancer drugs with genome‐wide loss‐of‐function screens in 484 cell lines to systematically investigate cellular drug mechanism‐of‐action. We observed an enrichment for positive associations between the profile of drug ...
Understanding the mechanism of drug action 药物作用机制的理解 药物是治疗或缓解疾病的一类化学物质。要想更好地使用药物,我们需要深入理解药物作用的机制。本文将介绍药物作用的基本原理,并解释药物与人体如何相互作用。 药物作用的基本原理 药物可以通过多种方式发挥作用,但它们基本上都会与人体内的化学反应相互作用,...
Cellular target engagement technologies enable quantification of intracellular drug binding, but the simultaneous assessment of drug-associated phenotypes is challenging. Here, the authors develop CeTEAM (cellular target engagement by accumulation of mutant), a platform that can simultaneously evaluate drug-...
Querying drug-induced gene expression profiles with machine learning method is an effective way for revealing drug mechanism of actions (MOAs), which is strongly supported by the growth of large scale and high-throughput gene expression databases. However, due to the lack of code-free and user ...
There are no adequate, well-controlled, head-to-head clinical trials comparing BRILINTA and thienopyridines in patients with acute ischemic stroke or high-risk CAD without a history of MI or stroke. The central role of platelets in thrombus formation ...