Mechanism of action describes the process by which a molecule, such as a drug, functions to produce a pharmacological effect. A drug’s mechanism of action may refer to its effects on a biological readout such as cell growth, or its interaction and modulation of its direct biomolecular target...
Bupropion is an antidepressant medication that prevents the reuptake of specific neurotransmitters in the brain. This lesson will discuss the mechanism of action and drug interactions of bupropion. Medication for Depression and Smoking Cessation Janice is a forty-year-old woman with a history of depr...
In this lesson we'll be learning about the antibiotic, vancomycin. After reading this article, you'll be able to explain how vancomycin clears up bacterial infections, as well as potential drug interactions and side effects. What Is Vancomycin?
Cellular target engagement technologies enable quantification of intracellular drug binding, but the simultaneous assessment of drug-associated phenotypes is challenging. Here, the authors develop CeTEAM (cellular target engagement by accumulation of mutant), a platform that can simultaneously evaluate drug-...
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美 英 na.作用动力 英汉 na. 1. 作用动力 例句 释义: 全部,作用动力 更多例句筛选
DRUG-eluting stentsObjective: This is the first study to explore the mechanism of colchicine in treating coronary artery disease using network pharmacology and molecular docking technology, aiming to predict the key targets and main approaches of colchicine in treating coronary arte...
resistant (MDR) HIV-1, FTR is well tolerated and virologically active. According to recent investigations, drug combination therapy can positively affect MDR-HIV. The mechanism of action, resistance, interaction, pharmacokinetics, pharmacodynamics, and safety of FTR has been highlighted in this review...
For decades, metformin has been the first-line drug for the treatment of type 2 diabetes, lowering blood glucose levels by inhibiting glucose production in the liver. Metformin also improves glucose uptake and use by muscle tissue. The effect of metformin on hepatic glucose production is most lik...
Abnormal levels of kynurenic acid (KYNA) in the human brain are believed to be connected to several central nervous system (CNS) diseases, therefore compounds which affect the production of this crucial metabolite are of interest in CNS drug development. The majority of KYNA production is accounted...