The antimicrobial era is threatened by high levels of antibiotic resistance, the limited number and disparate availability of effective antibiotics against diverse bacterial species, and reduced involvement by the pharmaceutical industry in the development of new anti-infectives. For the treatment of ...
antimicrobial-resistance of the A.Hydrophila strains was highly related to the antimicrobial usage in the field,from where the pathogens were isolated.By analyzing the correlation between the plasmid and its host bacterium's antimicrobial-resistance,it was found that 11 out of the 12 bacteria ...
Thompson1,2, Arnout P. Kalverda1,2, Anastasia Zhuravleva1,2 & Alex J. O'Neill1,2 Antibiotic resistance in clinically important bacteria can be mediated by proteins that physically associate with the drug target and act to protect it from the inhibitory effects of an antibiotic...
The widespread use of antibiotics in humans and animals has raised several concerns related to human and animal health.The principal area of concern has been the increasing emergence of antibiotic resistance phenotypes in both clinically relevant strains and normal commensal microbiots.The aim of this...
Antimicrobial Resistance of 914 Beta-Hemolytic Streptococci Isolated from Pharyngeal Swabs in Spain: Results of a 1-Year (1996–1997) Multicenter Surveilla... A nationwide susceptibility surveillance study of beta-hemolytic streptococcal isolates from pharyngeal swabs obtained in 11 Spanish hospitals betwe...
Antimicrobial resistance-conferring genes (ARGs) often co-localize to mobile genetic elements (MGEs), thereby conferring multidrug resistance and facilitating exchange between species3. As the current rate of discovery of new antimicrobial drug classes has been lagging since the golden era of ...
Antibiotic resistance is projected as one of the greatest threats to human health in the future and hence alternatives are being explored to combat resistance. Antimicrobial peptides (AMPs) have shown great promise, because use of AMPs leads bacteria to develop no or low resistance. In this revie...
The management of bacterial infections is becoming a major clinical challenge due to the rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome antibiotic resistance, antimicrobial peptides (AMPs) that are produced from the synthetic and natural sources demonstrate a broad...
Dr Matthew Dryden, consultant in microbiology and communicable disease at Royal Hampshire County Hospital and general secretary of the British Society for Antimicrobial Chemotherapy, said if the enzyme which creates nitric oxide could be inhibited, it could suppress the ability of the bacteria to ...
Dr Matthew Dryden, consultant in microbiology and communicable disease at Royal Hampshire County Hospital and general secretary of the British Society for Antimicrobial Chemotherapy, said if the enzyme which creates nitric oxide could be inhibited, it could suppress the ability of the bacteria to ...