Acquisition of exogenous DNA by pathogenic bacteria represents the basis for much of the acquired antimicrobial resistance in pathogenic bacteria. A more extreme mechanism to avoid the effect of an antibiotic is to delete the drug target, although this would be predicted to be rare since drug ...
Thompson1,2, Arnout P. Kalverda1,2, Anastasia Zhuravleva1,2 & Alex J. O'Neill1,2 Antibiotic resistance in clinically important bacteria can be mediated by proteins that physically associate with the drug target and act to protect it from the inhibitory effects of an antibiotic...
Author Correction: Computational Analysis of the Molecular Mechanism of RamR Mutations Contributing to Antimicrobial Resistance in Salmonella entericaA correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper....
Thompson1,2, Arnout P. Kalverda1,2, Anastasia Zhuravleva1,2 & Alex J. O'Neill1,2 Antibiotic resistance in clinically important bacteria can be mediated by proteins that physically associate with the drug target and act to protect it from the inhibitory effects of an antibiotic...
Baker SJ, Payne DJ, Rappuoli R, De Gregorio E (2018) Technologies to address antimicrobial resistance. Proc Natl Acad Sci USA 115(51):12887–12895.https://doi.org/10.1073/pnas.1717160115 ArticleCASPubMedPubMed CentralGoogle Scholar Blair JMA, Webber MA, Baylay AJ, Ogbolu DO, Piddock LJV...
Tigecycline resistanceeravacyclinemigratory birdsomadacyclinePlasmid-mediated antimicrobial resistance has emerged as one of the principal global issues, posing significant threats to public health. Herein, we reported a mobile tigecycline resistance mechanism Tet(X4) on both plasmid and chromosome in ...
U. Hofer The cost of antimicrobial resistance Nat. Rev. Microbiol., 17 (2019), p. 3 CrossrefView in ScopusGoogle Scholar Imai et al., 2019 Y. Imai, K.J. Meyer, A. Iinishi, Q. Favre-Godal, R. Green, S. Manuse, M. Caboni, M. Mori, S. Niles, M. Ghiglieri, et al. A ...
/ International Journal of Antimicrobial Agents 32 (2008) 199–206 resistance was only based on reduction of vaccine serotypes. Moreover, a further increase in fluoroquinolone resistance was observed in serotypes not covered by the vaccine. This finding indicates a continued selection pressure because...
Antibiotic resistance is mediated through several distinct mechanisms, most of which are relatively well understood and the clinical importance of which has long been recognized. Until very recently, neither of these statements was readily applicable to
Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it Article 18 January 2024 Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A Article Open access 14 July 2023 Macrolones target bacterial riboso...