Matsuzaki, "Ursodeoxycholic acid: mech- anism of action and novel clinical applications," Hepatology Research, vol. 38, no. 2, pp. 123-131, 2008.Ikeqami T,,Matsuzaki Y.Ursodeoxycholic acid:Mechanism of action and novel clinical app lications[ J ]. Hepatology Research . 2008...
Induction of CYP3A has been suggested as a mechanism of action of ursodeoxycholic acid. However, this enzyme interaction requires further investigation. General Function A cytochrome P450 monooxygenase involved in the metabolism of sterols, steroid hormones, retinoids and fatty acids (PubMed:10681376, Pu...
Ursodeoxycholic acid Sucralfate can cause a decrease in the absorption of Ursodeoxycholic acid resulting in a reduced serum concentration and potentially a decrease in efficacy. Vaborbactam Sucralfate may decrease the excretion rate of Vaborbactam which could result in a higher serum level. Vadadustat...
Genome Analysis Reveals a Synergistic Mechanism of Ursodeoxycholic Acid and Jasminoidin in Mice Brain Repair After Ischemia/Reperfusion: Crosstalk Among Mu... Genome Analysis Reveals a Synergistic Mechanism of Ursodeoxycholic Acid and Jasminoidin in Mice Brain Repair After Ischemia/Reperfusion: Crosstalk ...
Transforming growth factor beta1 (TGF-beta1)-induced hepatocyte apoptosis is associated with activation of E2F transcription factors and p53 stabilization through Mdm-2, thus potentially modulating a number of target genes. In previous studies, we have shown that ursodeoxycholic acid (UDCA) prevents ...
Chemoprevention of colon cancer by ursodeoxycholic acid: A possible mechanism of action: D. Earnest(1), A. Batta(3), H. Holubec(1), C. Jolley(1), T. Brasitus(2), G. Salen(3), Univ. of Arizona(1), Univ. of Chicago(2) and New Jersey Medical School(3)...
For bile acid metabolism, we selected 12 bile acids (two of which were potential biomarkers in nontargeted metabolomics) for quantitative analysis. The quantitative results of bile acids showed that after Qishen granules treatment, the contents of bile acids such as ursodeoxycholic acid and ...
The role of Ursodeoxycholic acid in non-alcoholic steatohepatitis: a systematic review Background Non-alcoholic steatohepatitis (NASH) is a condition that occurs during the progression of non-alcoholic fatty liver disease. Effective therapy f... Zun,Xiang,Yi-peng,... - 《Bmc Gastroenterology》 被...
Ursodeoxycholic acid or clofibrate in the treatment of non-alcohol-induced steatohepatitis: a pilot study Hepatology, 23 (1996), pp. 1464-1467 View PDFView articleView in ScopusGoogle Scholar [144] P.R. Holden, J.D. Tugwood Peroxisome proliferator-activated receptor alpha: role in rodent liver...
Ursodeoxycholic acid Cholestyramine can cause a decrease in the absorption of Ursodeoxycholic acid resulting in a reduced serum concentration and potentially a decrease in efficacy. Valdecoxib Cholestyramine can cause a decrease in the absorption of Valdecoxib resulting in a reduced serum concentration an...