Objective: The present study was designed to investigate the effect of ursodeoxycholic acid (UDCA), a drug widely utilised in the management of cholestatic conditions, on liver function tests and symptom relief in a group of patients with chronic hepatitis of different aetiologies. Patients and ...
greater extent than either drug alone. Ursodeoxycholic acid and its conjugates have considerably lower cholesterol-solubilising and dissolution propertiesin vitrothan chenodeoxycholic acid and its conjugates, using surgically acquired gallstones and in single and mixed bile salt systems. However, ursodeoxych...
Ursodeoxycholic acid (UDCA) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. UDCA is also a long-established drug, largely used for the ...
Ursodeoxycholic acid (Ursodeoxycholate) 是由肠道细菌转化 (cheno)脱氧胆酸而产生的一种次级胆汁酸,是肠道屏障完整性的关键调节因子,对脂质代谢至关重要。Ursodeoxycholic acid 作为信号分子,通过与胆汁酸激活的受体相互作用发挥作用,包括G蛋白偶联的胆汁酸受体5 (TGR5,GPCR19) 和法尼酯X受体 (FXR)。Ursodeoxycholic ac...
熊去氧胆酸 英文品名Ursodeoxycholic Acid 名称来源p-INNList-44,1980;r-INNList-21,1981; 化学表述3α,7β-Dihydroxy-5β-cholan-24-oic acid CA登记号128-13-2 分子式C24H40O4 结构式 品种类别消化系统>利胆药>胆酸衍生物;
Ursodeoxycholsäure; Acide ursodésoxycholique; Ácido ursodesoxicólico; 우르 소데 옥시 콜산; ウルソデオキシコール酸; (3α,5β,7β)-3,7-Dihydroxycholan-24-oic acid; (4R)-4-[(3R,5S,7S,8R,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,...
Due to its immunomodulatory effects, ursodeoxycholic acid is thought to contribute to autoimmune hepatitis treatment. This study investigated the efficacy of ursodeoxycholic acid administration in the treatment of patients with autoimmune hepatitis type 1, who were resistant to standard corticosteroid ...
1) 货号: U0800000; 2) 品牌: EP; 3) 英文品名: Ursodeoxycholic acid ; 4) 中文品名: 熊去氧胆酸 EP标准品; 5) CAS No. ; 6) 规格; 100 mg 甄准免费 公司简介 上海甄准生物科技有限公司(简称甄准)专业提供科研试剂产品,主要包括高端化学试剂、生物学试剂、分析标准品、对照品、标准物质等,应用覆盖药物...
No adverse effects of therapy were noted. The improvements in the clinical and biochemical parameters and tolerability of the drug suggest that ursodeoxycholic acid is a safe and effective treatment in children with intrahepatic cholestasis. 展开 ...
Drug Interactions (1) In combination with chenodeoxycholic acid, the effect of promoting cholesterol level and de-saturation in bile were more than single drugs. The effect is also greater than that of the sum of the two drugs. (2) This product is not suitable taken together with cholestyram...