transient D2 receptor antagonism (such as that attained with, for example, quetiapine and clozapine) is sufficient to obtain an antipsychotic effect, while permanent D2 receptor antagonism (as is caused by conventional antipsychotics) increases the risk of adverse effects such as extrapyramidal ...
Article: Clinical studies on the mechanism of action of clozapine: the dopamine-serotonin hypothesis of schizophrenia
was to provide important insights into the mechanism of action of clozapine and examine its associations with genes related to the etiology of schizophrenia... Park Kyungtaek,Kang Nuree,Huh Seong-Hoo,... - International Journal of Neuropsychopharmacology 被引量: 0发表: 2025年 Insights into the...
The mechanism of action of carbamazepine appears to be similar to that of A. benzodiazepines. B. valproate. C. phenytoin. D. ethosuximide. The...Become a member and unlock all Study Answers Start today. Try it now Create an accou...
Clozapine Minocycline may increase the central nervous system depressant (CNS depressant) activities of Clozapine. Cocaine The risk or severity of methemoglobinemia can be increased when Minocycline is combined with Cocaine. Codeine Minocycline may increase the central nervous system depressant (CNS depress...
Clozapine The metabolism of Colchicine can be decreased when combined with Clozapine. Cobicistat The serum concentration of Colchicine can be increased when it is combined with Cobicistat. Cobimetinib The serum concentration of Cobimetinib can be increased when it is combined with Colchicine. Colistimethate...
Antipsychotic Agents/adverse effectsAntipsychotic Agents/therapeutic useBenzodiazepinesBenzodiazepines/therapeutic useClozapineClozapine/therapeutic use... CA Lobos,K Komossa,C Rummel-Kluge,... - 《Cochrane Database of Systematic Reviews》 被引量: 533发表: 2009年 Long-term Therapeutic Use of Benzodiazepines...
of action in the lipid phase of the membrane.4The effect of bath-application of low concentrations of DHAVM on inside-out patches was investigated under... RJ Martin,AJ Pennington - 《British Journal of Pharmacology》 被引量: 137发表: 1989年 Comparison of the effects of clozapine, chlorpromaz...
Millan M. Competitive antagonism of serotonin (5-HT)2C and 5-HT2A receptormediated phosphoinositide (PI) turnover by clozapine in the rat: a comparison to other antipsychotics. 1994. Sweet R, Pollock B, H. Mulsant B, Rosen J, Sorisio D, Kirshner M, et al. Pharmacologic profile of ...
Clozapine Clozapine may decrease the antihypertensive activities of Minoxidil. Conivaptan The risk or severity of adverse effects can be increased when Minoxidil is combined with Conivaptan. Cryptenamine Minoxidil may increase the hypotensive activities of Cryptenamine. Cyclopenthiazide The therapeutic effi...