The mechanism of action of clozapine in relation to its clinical advantages. In: Meltzer, HY (ed): Novel antipsychotic drugs. New York: Raven Press; 1992 (pp 1-13).MELTZER HY. The mechanism of action of Clozapine in relation to its clinical ...
Article: Clinical studies on the mechanism of action of clozapine: the dopamine-serotonin hypothesis of schizophrenia
Clozapine Clozapine may decrease the antihypertensive activities of Minoxidil. Conivaptan The risk or severity of adverse effects can be increased when Minoxidil is combined with Conivaptan. Cryptenamine Minoxidil may increase the hypotensive activities of Cryptenamine. Cyclopenthiazide The therapeutic effi...
Clozapine Clozapine may decrease the antihypertensive activities of Captopril. Codeine The excretion of Captopril can be decreased when combined with Codeine. Colchicine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Captopril is combined with Colchicine. Conivap...
It is no longer tenable to attribute all the antipsychotic action of antipsychotic drugs to dopamine (DA) D2 receptor blockade and subsequent development of depolarization inactivation of the mesolimbic or mesocortical DA neurons. The chief evidence for this position is that clozapine (CLOZ) does no...
Using electrophysiological techniques we have found that clozapine, like typical antipsychotic drugs, inactivates most midbrain dopamine cells secondary to the induction of depolarisation block. However, unlike classical antipsychotic drugs, clozapine does not inactivate the nigrostriatal dopamine system. ...
Article: Haloperidol and clozapine treatment and their effect on M-chlorophenylpiperazine-mediated responses in schizophrenia: implications for the
Clozapine-Induced Mitochondria Alterations and Inflammation in Brain and Insulin-Responsive Cells Metabolic syndrome (MetS) is a constellation of factors including abdominal obesity, hyperglycemia, dyslipidemias, and hypertension that increase morbidity... CS Ver?Nica,DL Heart,PR Madelaine,... - 《Plos...
This chapter presents the studies on the mechanisms of the dopamine-mediated inhibition of prolactin secretion. Evidence has been presented that suggests t... SWJ Lamberts,RM Macleod - 《Proc Soc Exp Biol Med》 被引量: 626发表: 1978年 Clinical studies on the mechanism of action of clozapine:...
Clozapine Clozapine may decrease the excretion rate of Sucralfate which could result in a higher serum level. Colchicine Sucralfate may decrease the excretion rate of Colchicine which could result in a higher serum level. Colistimethate Colistimethate may decrease the excretion rate of Sucralfate which ...