Mdr 2 knockout mice link biliary phospholipid deficiency with small bile duct destruction. Hepatology 1994;19:1528-1531.Leveille-Webster, C. R. & I. M. Arias (1994) Mdr 2 knockout mice link biliary phospholipid deficiency with small bile duct destruction. Hepatology, 19, 1528-31....
Mdr2 knockout mice is a liver disease model, which causes cholestasis due to the lack of phospholipids in the bile. At present, it is not only used for the study of human homologous MDR3 gene, but also widely used as an animal model of liver diseases such as primary sclerosing cholangiti...
Chronic Administration of Nicotine Increases Biliary Damage and Hepatic Fibrosis in Mdr2 Knockout (KO) MiceIn chronic cholestatic liver diseases, cholangiocytes, through the products of their cellular activation, are suggested to be an important link between biliary injury and the subepithelial ...
- 1995 - A316 - www.sciencedirect.comdoi:10.1016/0270-9139(95)94988-7None
- 1995 - A1192 - www.sciencedirect.comdoi:10.1016/0016-5085(95)29070-2NoneGastroenterology
Targeting senescent cholangiocytes and activated fibroblasts with B‐cell lymphoma‐extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout ( Mdr2 ?/? Mdr2 ?/? ?/? ) mice 来自 国家科技图书文献中心 喜欢 0 阅读量: 8 摘要: Cholangiocyte senescence has been linked ...
2月5日美国中部德克萨斯退伍军人医疗保健系统在HEPATOLOGY上发表了文章“Amelioration of Ductular Reaction by Stem Cell Derived Extracellular Vesicles in MDR2 knockout mice via let-7 microRNA”,文章评估了肝干细胞衍生的EV(LSCEV)的含量,将它们的miRNA含量与从肝细胞分离的EV的那些进行了比较,并评估了这些...
Molecular mechanisms of liver carcinogenesis in the mdr2-knockout mice. Mol. Cancer Res. 2007, 5, 1159–1170. [Google Scholar] [CrossRef] [PubMed] Hines, J.E.; Johnson, S.J.; Burt, A.D. In vivo responses of macrophages and perisinusoidal cells to cholestatic liver injury. Am. J....
Wild type and hsf1 knockout mouse embryonic fibroblast (HSF1+/+ and HSF1−/− MEF) cells were provided by Dr. Ivor J. Benjamin (University of Utah, Salt Lake City, UT). MEF (HSF1+/+ and HSF1−/− MEF) cells were cultured in Dulbecco’s minimal essential medium (DMEM) ...
Depletion of the HDC/histamine axis ablates tumor formation, angiogenesis, EMT and inflammation in Mdr2 knockout micedoi:10.1016/s0168-8278(18)31624-6L. KennedyJ. DemievilleL. HargroveV. MeadowsG. AlpiniH. FrancisElsevier BVJournal of Hepatology...