We offer knockin mouse model service from strategy design to F1 mice. ESC Gene knockin services include conditional knockin, humanized & Rosa26 knockin.
(2007) Tau-4R suppresses proliferation and promotes neuronal differentiation in the hippocampus of tau knockin/knockout mice. FASEB J. 21, 2149 -2161Sennvik, K. , Boekhoorn, K. , Lasrado, R. , Terwel, D. , Verhaeghe, S. , Korr, H. , Schmitz, C. , Tomiyama, T. , Mori, H...
Knockout and knockin mice to investigate the role of nicotinic receptors in the central nervous system Pharmacological manipulations of nicotinic transmission have long been the only way to investigate the role of nicotinic acetylcholine receptors (nAChRs) in the brain. More recently, however, the use...
4. TurboKnockout®mouse production Introduce targeted ES cells into host embryos, followed by transfer into surrogate mothers. The resulting TurboKnockout®heterozygous mutants are 100% derived from the injected ES cells. We will aim to generate a minimum of 3 mice. ...
00 pm). Genotypes of Dyrk1a-KI HT mice were determined by PCR using the following primer pairs: wild-type [WT] allele (413 bp): 5’-557GAG AAA GAG AGC TGT TTG CCT TCC G-3’ (forward) and 5’-CAA GCA GTT ACA558AGT TCC AGG CTC C-3’ (reverse); knockout (KO) allele ...
Neurogenesis Is Reduced but Astrogenesis Increased in ApoE-KO Mice To analyze hippocampal neurogenesis and astrogenesis as a consequence of apoE genotype, we followed the survival and differentiation of newborn cells over time in 6- to 7-month-old mice with knockout for apoE (apoE-KO) or with...
Identification of cells expressing somatostatin receptor 2 in the gastrointestinal tract of Sstr2 knockout/lacZ knockin mice. J Comp Neurol. 2002; 454 :329–340. doi: 10.1002/cne.10466. [ Cross Ref ]Allen JP , Canty AJ , Schulz S , Humphrey PPA , Emson PC , Young HM ( 2002 ). ...
294 Generation of endoplasmic reticulum protein 44 (ERP44) knockout/knockin mice to investigate the role of ERP44 in calcium signaling and ER stress in cardiomyocytes - Canadian Journal of Cardiologydoi:10.1016/j.cjca.2011.07.222D.Y. Wang
Animal Models For Disease--Knockout, Knockin And Conditional Mutant Mice David F. LePage and Ronald A. ConlonLepage, David FConlon, Ronald A
Allen JP, Hathway GJ, Clarke NJ et al (2003) Somatostatin receptor 2 knockout/lacZ knockin mice show impaired motor coordination and reveal sites of somatostatin action within the striatum. Eur J Neurosci 17:1881-1895Allen, J.P., Hathway, G.J., Clarke, N.J., Jowett, M.I., Topps, ...