Knockout and knockin mice to investigate the role of nicotinic receptors in the central nervous system Pharmacological manipulations of nicotinic transmission have long been the only way to investigate the role of nicotinic acetylcholine receptors (nAChRs) in the brain. More recently, however, the use...
Humanized mice - knockin mouse model with an endogenous gene replaced by a human gene or genomic sequence - are used in human gene function and disease research.
We offer knockin mouse model service from strategy design to F1 mice. ESC Gene knockin services include conditional knockin, humanized & Rosa26 knockin.
Enamel Defects in Enamelin Knockout/LacZ Knockin MiceJ.C.C. HU
1. Somatostatin receptor 2 knockout/lacZ knockin mice show impaired motor coordination and reveal sites of somatostatin action within the striatum. [J] . Allen JP, Hathway GJ, Clarke NJ, The European Journal of Neuroscience . 2003,第9期 机译:生长抑素受体2基因敲除/ lacZ基因敲除小鼠显示出运动...
Somatostatin receptor 2 knockout/lacZknockin mice show impaired motor coordination and reveal sites of somatostatin action within the striatum Emson PC (2003) Somatostatin receptor 2 knockout/lacZ knockin mice show impaired motor coordination and reveal sites of somatostatin action within the striatu.....
AMBN mutations causing hypoplastic amelogenesis imperfecta and Ambn knockout‐NLS‐lacZ knockin mice exhibiting failed amelogenesis and Ambn tissue‐specificityAmbn‐/‐Amelx‐/-amelinameloblastinamelogenindental enamel formationmatrix proteinsmineralization...
Instead, individual crystallites seemed to spill out of the enamel when fractured. These results demonstrate that Klk4 is essential for the removal of enamel proteins and the proper maturation of enamel crystals. 展开 关键词: Dental Enamel Animals Mice, Inbred C57BL Mice Kallikreins Tomography, X...
demonstrating thatMyh11-CreERcould be used for efficient gene knockout in the SMC lineage-specific cells. Altogether, the current study reports two highly efficient SMC-specific Cre knock-in mice:Myh11-CreandMyh11-CreERthat can be used for both genetic lineage tracing and genome editing in SMCs...
Allen JP, Hathway GJ, Clarke NJ et al (2003) Somatostatin receptor 2 knockout/lacZ knockin mice show impaired motor coordination and reveal sites of somatostatin action within the striatum. Eur J Neurosci 17:1881-1895Allen JP, Hathway GJ, Clarke NJ et al. Somatostatin recep- tor 2 knockout...