[5] Li B, Cheng Q, Li Z, et al. p53 inactivation by MDM2 and MDMX negative feedback loops in testicular germ cell tumors[J]. Cell Cycle, 2010, 9(7): 1411-1420. [6] Traweek RS, Cope BM, Roland CL, Keung EZ, ...
参考资料: [1]Lyubomir T. Vassilev et al. In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2.Science(2004). [2]Jiajia Zhou et al. The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell...
Nag S, Qin J, Srivenugopal KS, Wang M, Zhang R. The MDM2-p53 pathway revisited . J Biomed Res . 2013. July; 27 ( 4 ):254–71. doi: 10.7555/JBR.27.20130030Nag S, Qin J, Srivenugopal KS, Wang M, Zhang R (2013) The MDM2-p53 pathway revisited . J Biomed Res 27 : 254–...
【3】Tyler, Andrew F. , et al. "Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide." Journal of the American Chemical Society 129.9(2007):2456-7.doi:10.1021/ja0693587 【4】Bernal, Federico , et al. "A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p...
study of the MDM2 inhibitor AMG 232 with or without trametinib in relapsed/refractory acute myeloid leukemia，2019 9.Identification and characterization of the first small molecule inhibitor of MDMX，2010 10.Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization，2012 ...
Conclusions Therisk and prognosis of colorectal cancer are closely related to the MDM2鄄p53 signaling pathway. p53 can be used as apotential target for the prognosis and treatment of colorectal cancer.【Key words】 Colorectal cancer; p53; Murine double minute 2; Clinicopathological features;Signaling...
9.Identification and characterization of the first small molecule inhibitor of MDMX,2010 10.Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization,2012
This review focuseon the progress in studying on the relationship between the ribosomal protein on the MDM2-p53 regulatory pathway and its roles incancer therapy. KEYWORDS: MDM2- p53 pathway ;Ribosomal protein;Ribosomal stress;Cancer therapy Corresponding author: Jin Yan. E-mail: nc.ude.umbrh....
【3】Tyler, Andrew F. , et al. "Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide."Journal of the American Chemical Society129.9(2007):2456-7. doi:10.1021/ja0693587 【4】Bernal, Federico , et al. "A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53....
328ARF-mdm2-p53 的相互作用途径林静朱明华(审校)lnteractive Pathway of ARF-mdm2-p53Lin Jing, Zhu Ming-hua第二军医大学长海医院病理科,上海, 200433Department of Pathology, ChanghaiHospital, The Second MilitaryMedical Uniuersity,Shanghai,200433, P. R. China通讯作者: 朱明华Correspondence to: Zhu Ming-...