Download: Download full-size image Fig. 1. Energetic metabolism in breast carcinoma cells with different aggressiveness. BM-prone MDA-MB-231 cells were metabolically compared with MCF7 cells that are not able to form BM. (a) Representative graphs showing extracellular acidification rate (for ECAR:...
MDA-MB 231 overexpressing VEGF165 (V165) or control cells (cV) was carried out with AffymetrixGeneChip Human Gene 1.0 ST arrays. Similarly, MDA-MB-231-derived lung metastases obtained after the intracardiac injection of V165, V189 and cV clones, respectively, V165M, V189M or control clones ...
FULL PAPER British Journal of Cancer (2015) 113, 773–785 | doi: 10.1038/bjc.2015.267 Keywords: VEGF isoforms; metastasis; colonisation; breast cancer MDA-MB-231 breast cancer cells overexpressing single VEGF isoforms display distinct colonisation characteristics Melanie Di Benedetto*,1,2,7, Aurore...
The use of MDA-MB-231 cells in nanoplastic research is conducted for the following reasons: this cell line is a highly aggressive, triple-negative breast cancer (TNBC) model characterized by poor differentiation and the absence of estrogen receptor (ER), progesterone receptor (PR), and HER2 (h...
Comparing the IC50 values of nrCap18 and DOX in MDA-MB 231 and MCF-10A cell lines. DOX: doxorubicin. ns P > 0.05 and **P < 0.01. DOX: doxorubicin. Full size image Selectivity of nrCap18 for cancer cells The selectivity of nrCap18 for cancer cells (MDA-MB 231) was invest...
DRE was applied to MDA-MB-231 cells in doses of 0.5, 1.0, 2.5 and 5 mg/mL compared to the MDA-MB-231 control, which had 100% viability. The results (Fig. 3A) revealed that DRE significantly reduced the viability of the cells in a dose-dependent form; treatment with 5, 2.5, 1.0...
p65 is a pivotal anti-apoptotic factor that can reverse celecoxib-induced growth inhibition in MDA-MB-231 cells.Background Breast cancer is currently the most common form of cancer affecting women and the sixth leading cause of cancer-related death among women in China [1]. Despite intensive ca...
Full size image Since BDNF in its mature form is secreted into the culture media of MDA-MB-231, this protein has the potential to affect adjacent cells associated with metastasis such as endothelial cells, thus there is a possibility of a paracrine effect. Therefore next we attempted to determ...
crispus[11], reported to induce apoptosis of MDA-MB-231 cells[29] and increase caspase-8 activity in MCF-7 and MDA-MB-231 cells in association with elevation of Fas protein expression[30]. Alternatively, caspase-8 cleaves BH3-only protein, Bid, to generate the truncated form of Bid, t...
(C) Proliferation assay results sfor MDA-MB-231 cells after LARP6 overexpression. (D) Cell invasion results for MDA-MB-231 cells after LARP6 overexpression. Full size image LARP6 regulates the transcriptome in MDA-MB-231 cells We carried out RNA-seq on cells from the OE-LARP6 group and...