HZ982Hu01 PP2A癌症抑制抑制因子(CIP2A)重组蛋白 Recombinant Cancerous Inhibitor Of PP2A (CIP2A) Homo sapiens (Human) HZ031Mu02 Misato同源物1(MSTO1)重组蛋白 Recombinant Misato Homolog 1 (MSTO1) Mus musculus (Mouse) HZ092Ra01 透明质酸氨基葡糖苷酶1(HYAL1)重组蛋白 Recombinant Hyaluronoglucosamini...
A Novel Epidermal Growth Factor Receptor Inhibitor Promotes Apoptosis in Non–Small Cell Lung Cancer Cells Resistant to Erlotinib Non-small cell lung cancer (NSCLC) with activating mutations in the epidermal growth factor receptor (EGFR) responds to EGFR tyrosine kinase inhibitors suc... de La Motte...
细胞凋亡抑制蛋白1(Inhibitorofapoptosisprotein1,c-IAP1)为存在于细胞核与细胞质中对细胞生长起着负调控作用,通过调节caspase酶的活性及NF-κB信号通路而起作用;也可通过调节Rho家族中Rac1等的活性而参与肿瘤的浸润转移。c-IAP1的抗凋亡机制促进了肿瘤的形成并可能参与了化疗的耐药。 肿瘤的发生与细胞周期DNA复制异...
Abbreviations (with mutated genes in white): AAAS, achalasia-Addisonianism-alacrimia (triple A) syndrome gene; AIRE, autoimmune regulator; ANT, adenine nucleotide translocator; ATAD3, ATPase family AAA domain-containing protein 3; CDKN1C, cyclin-dependent kinase inhibitor 1C; CYP11A1, ...
Ciprofloxacin is an inhibitor of the Mcm2-7 replicative helicase. Biosci. Rep. 33(5), e00072. https://doi.org/10.1042/BSR20130083 (2013). Article CAS PubMed PubMed Central Google Scholar Mosquera, J. M. et al. Concurrent AURKA and MYCN gene amplifications are harbingers of lethal tre...
inhibitor后,He La细胞增殖活性显著高于对照组,差异有统计学意义(P<0.05);转染miR-18 6-3p mimcs后,He La细胞活性增殖显著低于对照组,差异有统计学意义(P<0.05);敲除MCM2(转染si MCM2)后,He La细胞活性增殖显著低于对照组,差异有统计学意义(P<0.05).Transwell实验结果显示,miR-18 6-3p inhibit...
In this review, we summarize the currently available data regarding the regulatory mechanisms and functional consequences of MCM phosphorylation and seek the probability that protein kinase inhibitor can be used therapeutically to target MCM phosphorylation in cancer. 展开 关键词:...
MP470 was chosen as an inhibitor of the interaction between USP31 and RUNX1, results suggested that the USP31 protein acts through deubiquitination to affect the RUNX1 protein. The methylation level of USP31 was negatively correlated with the transcription level (Supplementary Fig. 6A) and its ...
Anti-PAI-1(plasminogen activator inhibitor 1) 纤溶酶原激活物抑制因子抗体 Anti-PAI-2(plasminogen activator inhibitor 2) 纤溶酶原激活物抑制因子2抗体 Anti-phosphor-PAK1+PAK2+PAK3 (pSer141) 抗磷酸化p21激活激酶1/2/3抗体 Anti-phospho-PAK1(pSer144) 抗磷酸化p21激活激酶1抗体 ...
inhibitor.G,HANXA4 and MCM2 levels inshCont-andshANXA4-transduced HBV-infected HepG2-NTCP cells.IANXA4, p62, and MCM2 expression in HBV-infected HepG2-NTCP cells transduced withshANXA4and treated with an autophagy inhibitor.JProtein interactions were detected by immunoprecipitation in HepG2.2...