malonyl-CoAfatty acid synthetaseacetyl-CoA carboxylaseShort-term control of fatty acid synthesis in vivo may result from inhibition of acetyl-CoA carboxylase by long chain acyl-CoA. Long-term control may result from change in the level of fatty acid synthetase....
Malonyl-CoA is an intermediary metabolite that plays a key role in fatty acid synthesis. It acts as a substrate for the formation of palmitate and also inhibits fatty acid oxidation. AI generated definition based on: Encyclopedia of Biological Chemistry (Second Edition), 2013 ...
CHS catlyze the reaction of malonyl-coA and coumaroyl-coA to chalcone, and is the first enzyme that leads to the synthesis of flavonoids. Regulation Mechanism of Chlorogenic Acid Accumulation during the Floral Organ Development of Lonicera confusa Other intermediary metabolites of fatty acid metabolism...
Hepatic malonyl-CoA levels of fed, fasted and diabetic rats as measured using a simple radioisotopic assay. The role of malonyl-coa in the coordination of fatty acid synthesis and oxidation in isolated rat hepatocytes Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carn...
Malonyl-CoA is an important central metabolite serving as the basic building block for the microbial synthesis of many pharmaceutically interesting polyketides, but also fatty acid–derived compounds including biofuels. Especially Saccharomyces cerevisiae , Escherichia coli , and Corynebacterium glutamicum have...
On the mechanism of malonyl-CoA-independent fatty acid synthesis. I. The mechanism of elongation of long-chain fatty acids by acetyl-CoA 1. 1. The crystallization of thiolase specific for long-chain β-keto-CoA derivatives (acyl-CoA:acetyl-CoA C-acyltransferase, EC 2.3.1.16) from ox liver ...
Related to Malonyl:malonic acid,malate Mal´o`nyl n.1.(Chem.)A divalent diacyl radical, CH2.(CO)2, from malonic acid. Webster's Revised Unabridged Dictionary, published 1913 by G. & C. Merriam Co. Want to thank TFD for its existence?Tell a friend about us, add a link to this pa...
Bacterial fatty acid synthesis in Escherichia coli is initiated by the condensation of an acetyl-CoA with a malonyl-acyl carrier protein (ACP) by the β-ketoacyl-ACP synthase III enzyme, FabH. E. coliΔfabH knockout strains are viable because of the yiiD gene that allows FabH-independent...
On the mechanism of malonyl-CoA independent fatty acid synthesis. II. Isolation, properties and subcellular location of trans-2,3-hexenoyl-CoA and trans-2,... 1. 1. The separation by zonal centrifugation of two enoyl-CoA reductases located in microsomes and mitochondria of rat liver is descr...
The genes for pyruvate dehydrogenase (aceE) and acetyl-CoA carboxylase (accA), which are the enzymes that catalyze the first step in the synthesis of fatty acids in Escherichia coli MG1655, were cloned. That is, the E. coli strains were midterm recombinant strains to produce fatty acid. The...