methylation in the human transcriptome Hanxiao Sun1,5, Kai Li1,2,3,5, Xiaoting Zhang1, Jun'e Liu1, Meiling Zhang1, Haowei Meng 1 & Chengqi Yi 1,3,4✉ N6,2′-O-dimethyladenosine (m6Am), a terminal modification adjacent to the mRNA cap, is a newly discovered reversible RNA ...
J. An optimized kit-free method for making strand-specific deep sequencing libraries from RNA fragments. Nucleic Acids Res . 43, e2 (2015) Article Google Scholar Li, B. & Dewey, C. N. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC ...
2022, Science Translational Medicine m<sup>6</sup>A RNA methylation: from mechanisms to therapeutic potential 2021, EMBO Journal The emerging roles of N6-methyladenosine (m6A) deregulation in liver carcinogenesis 2020, Molecular Cancer View all citing articles on Scopus ...
Briefly, the H3 (histone 3) was used as the control and the reference for quantification of the H3K27me3 modification. Measurement of the KDM6 demethylase activity The demethylase activity of KDM6s were measured by the JMJD3/UTX demethylase activity assay colorimetric kit (Epigentek). Briefly,...
The analysis also involved the identification and quantification of geometric and topological features. It was discovered that surface pockets and cavities play a role in hindering the functional development of protein targets. The methyltransferase enzymes were shown to possess several central pockets and...
J. An optimized kit-free method for making strand-specific deep sequencing libraries from RNA fragments. Nucleic Acids Res . 43, e2 (2015) Article Google Scholar Li, B. & Dewey, C. N. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC ...