M1 polarization of macrophages promotes stress‐induced hair loss via interleukin‐18 and interleukin‐1βhair follicle stem cellshair lossimmunemacrophagestressStress‐induced hair loss is a prevalent health concern, with mechanisms that remain unclear, and effective treatment options are not yet ...
摘要 Phenotypicpolarizationof macrophages is regulated by a milieu of cues in the local tissuemicroenvironment. Although much is known about how soluble factors influence macrophage polarization, relatively little is known about howphysical cuespresent in the extracellular environment might modulate proinflamma...
Macrophages are innateimmunecellsthatadopt diverse activation states in response to their microenvironment. Editingmacrophage activationto dampeninflammatory diseasesby promoting therepolarizationof inflammatory (M1) macrophages toanti-inflammatory(M2) macrophages is of high interest. Here, we find that mouse a...
Liu Q, Li J, Zong Q, et al. Interferon-induced polarization of M1 macrophages mediates antiviral activity against the hepatitis B virus via the hepcidin-ferroportin axis[J]. Int Immunopharmacol. 2024, 134: 112219.
小鼠巨噬,也可以参考此方法,也可以加上F4/80、CD11b作为上级门,也可以加上巨噬细胞功能标记,可参考mTORC1-mediated polarization of M1 macrophages and their accumulation in the liver correlate with immunopathology in fatal ehrlichiosis [4]。 但是,有不少FLOWER仍然反映,CD206实在染不好啊,分不开,那怎么办...
Molecular mechanisms that influence the macrophage M1-M2 polarization balance. As an essential component of innate immunity, macrophages have multiple functions in both inhibiting or promoting cell proliferation and tissue repair. Div... Nan,Wang,Hongwei,... - 《Frontiers in Immunology》 被引量: ...
Fig.4 Knockout of ficolin inhibits the polarization of M1 macrophagesin vitro A:The protein of iNOS expression after LPS stimulation in BMDM derived from WT andficolinknockout mice;B: Statistical analysis of iNOS expression ...
Homocysteine promotes proliferation and M1 polarization of mouse macrophages through up-regulating Rap1A expression YANG Ya-li 1,2,3TIAN Rong 1YUAN Yin 1WANG Yan-jia 1YANG Xiao-ling 1,2,3 (1. School of Basic Medical Sc...
图片来源:Haloul, M., Oliveira, E.R.A., Kader, M. et al. mTORC1-mediated polarization of M1 macrophages and their accumulation in the liver correlate with immunopathology in fatal ehrlichiosis. Sci Rep 9, 14050 (2019). http...
Polarization of macrophages is a characteristic of both cancer and infection, and may promote progression or resolution of disease. However, the role of macrophages and their polarization during H. pylori infection has not been well defined. By using a mouse model of infection and gastric biopsies...