Molecular mechanisms and treatment of radiation-induced lung fibrosis [J]. Curr Drug Targets, 2013, 14 (11): 1347-1356.DingNH; Li JJ; Sun LQ.Molecular mechanisms and treatment of radiation-induced lung fibrosis.Curr Drug Targets.2013.1347-1356...
steroids have shown efficacy as a treatment option for RP grade 2 [76]. However, few studies have assessed the efficacy of inhaled steroids in cancer patients. It is well-known that patients with chronic disease (radiation fibrosis) are unlikely to benefit from glucocorticoid therapy [60]. Fig...
Radiation-induced changes in lung tissue and development of fibrosis determined by quantitative morphometric methods 来自 掌桥科研 喜欢 0 阅读量: 23 作者:R Kraus,F Steinberg,B Rehn,J Bruch,C Streffer 摘要: This study presents results of morphometric investigations of mouse lungs after single ...
Radiation pneumonia is usually diagnosed by exclusion, medicines including steroids, ACE inhibitors and theophylline have formed the cornerstone of treatment [27]. Growing evidence showed that radiation-related pneumonia and fibrosis may be the results of the interaction between chronic inflammation and ...
Although there is no fixed treatment dosage, inhaled steroids have shown efficacy as a treatment option for RP grade 2 [76]. However, few studies have assessed the efficacy of inhaled steroids in cancer patients. It is well-known that patients with chronic disease (radiation fibrosis) are ...
Often, the inflammation resolves with minimal parenchymal changes; however, the inflammatory process may progress to parenchymal fibrosis. The risk of radiation lung injury appears to be best predicted by the dose-volume histogram that is calculated from the total radiation dose delivered to a ...
radiation resistance, the overall survival rate of lung cancer patients is not ideal. There is an urgent need to develop new treatment strategies or new effective drugs to treat lung cancer. Ferroptosis, a novel type of programmed cell death, is different from the traditional cell death pathways...
Lung fibrosis (LF) is a chronic progressive, incurable, and debilitating condition of the lung, which is associated with different lung disease. Treatment options are still sparse. Nintedanib, an oral tyrosine kinase inhibitor, significantly slows the LF
Martin M, Remy J, Daburon F (1986) In vitro growth potential of fibroblasts isolated from pigs with radiation- induced fibrosis. Int J Radiat Biol 49: 821–828 CAS Google Scholar Martinet Y, Rom WN, Grotendorst GR, Martin GR, Crystal RG (1987) Exaggerated spontaneous release of platelet...
radiation;lung fibrosis;animal models;antifibrotic;therapeutic targets 1. Introduction Radiation therapy (RT) is performed in about 50% of all cancer patients at least once during their treatment course. Recently, with the development of computer and mechanical engineering, it has become increasingly im...