EGFR- mutated lung cancer in Li-Fraumeni syndrome. Lung Cancer 2014;85: 485-7.Vasiliki Michalarea,Matthew Calcasola,Paul Cane,Khalid Tobal,Louise Izatt,James Spicer.  EGFR-mutated lung cancer in Li-Fraumeni syndrome[J]. Lung Cancer . 2014 (3)...
Lung cancer is the most common cause of cancer-related deaths globally. Although smoking-related lung cancers continue to account for the majority of diagnoses, smoking rates have been decreasing for several decades. Lung cancer in individuals who have never smoked (LCINS) is estimated to be the...
People with Li-Fraumeni syndrome that inherit one mutant p53 allele and one WT p53 allele have an ~50% likelihood of developing cancer by the age of 35 and a ~90% risk of developing cancer throughout their lifetime [83]. Although over 2000 different mutations in the p53 gene have been ...
Lung cancer is the most common cause of cancer-related deaths globally. Although smoking-related lung cancers continue to account for the majority of diagnoses, smoking rates have been decreasing for several decades. Lung cancer in individuals who have never smoked (LCINS) is estimated to be the...
The Li-Fraumeni syndrome (LFS): a model for the initiation of p53 signatures in the distal Fallopian tube A candidate early precursor to pelvic serous cancer, the 'p53 signature', is commonly found in the benign mucosa of the distal Fallopian tube and harbours ... W Xian,A Miron,M Roh...
J. Natl Cancer Inst. 106, djt361 (2014). Article PubMed Google Scholar Mezquita, L. et al. High prevalence of somatic oncogenic driver alterations in patients with NSCLC and Li-Fraumeni syndrome. J. Thorac. Oncol. 15, 1232–1239 (2020). Article CAS PubMed Google Scholar Carrot-Zhang...
The potential applicability of specific carcinogen-derived biomarkers in chemoprevention trials against lung and oral cancer is discussed. At present, ther... SS Hecht - 《Iarc Scientific Publications》 被引量: 36发表: 2001年 Genomics Approaches to Lung Cancer Chemoprevention in Li Fraumeni Syndrome ...
Declining lung cancer rates among young men and women in the United States: A cohort analysis : Devesa SS, Blot WJ, Fraumeni JF Jr. Division of Cancer Etio... Declining lung cancer rates among young men and women in the United States: A cohort analysis : Devesa SS, Blot WJ, Fraumeni ...
Familial cancer accounts for 15–20% of total cancers,1 examples of which include Li–Fraumeni syndrome (OMIM: 151623), hereditary retinoblastoma (OMIM: 180200), familial breast cancer (OMIM: 604370) and Lynch Syndrome (OMIM: 120435). Familial lung cancers, however, are less common. Previous ...
J. Natl Cancer Inst. 106, djt361 (2014). Article PubMed Google Scholar Mezquita, L. et al. High prevalence of somatic oncogenic driver alterations in patients with NSCLC and Li-Fraumeni syndrome. J. Thorac. Oncol. 15, 1232–1239 (2020). Article CAS PubMed Google Scholar Carrot-Zhang...