作者构建了一个基于UCSC genome browser的组学可视化网站，整合40个数据集中的的染色质相互作用、CTCF结合、基因表达、组蛋白修饰、染色体开放区间、DNA甲基化、基因变异以及单细胞水平的基因表达等信息，并分析他们在正常细胞和肺癌细胞之间的差异。COVID-19患者的单细胞数据也被整合进网站。网站链接：http://www.lung...
Methylation of CpG islands in the promotor region is an important avenue for inactivation of p16. The mechanism of methylation of the p16 promotor region, however, has not been elucidated. Recent reports investigating p16 m...
参考报价: 1 - 4800 RMB(人民币) 型号: 肺癌DNA甲基化PCR芯片 Lung Cancer DNA Methylation PCR Array 品牌: 英拜生物 产地: 上海 关注度: 6 信息完整度: 样本: 典型用户: 暂无咨询留言 在线咨询 400-6699-117转1000产品简介产品推荐 Human Lung Cancer DNA Methylation PCR Array, Signature Panel: ...
Using tumor DNA methylomes to predict cancer metastasis to the brain Metastatic spread of cancer to the brain has a devastating effect on patient outcomes, yet identifying patients who will develop brain metastases is difficult in current clinical practice. We show that DNA methylation signatures from...
DNA methylation profiling revealed that GDNF, RARB, and HS3ST2 were methylated more frequently in cancer patients than in the control participants (P=0.0017, 0.0062, and 0.0193, resp.). Combined analysesindicatedthat 6 of 16 cancer patients (37.5%), but only 1 of 32 control individuals (3.1...
We compared smoking-related DNA methylation in lung adenocarcinoma (61 never smokers, 91 current smokers, and 238 former smokers) quantified with the Illumina450k BeadArray in The Cancer Genome Atlas with published large consortium meta-analyses of newborn and adult blood. We assessed whether CpG ...
Epigenetic basis of lung cancer—DNA methylation and tumor suppressor gene inactivation There is overwhelming evidence that tumor acquired promoter hypermethylation, leading to loss of expression of the associated gene, is a common event during the multistep pathogenesis of human lung cancer. Ove...
A phase III trial of topotecan and whole brain radiation therapy for patients with CNS-metastases due to lung cancer Brain metastases represent an important cause of morbidity in patients with lung cancer and are associated with a mean survival of less than 6 months. Thus... T Neuhaus,Y Ko,...
DNA methylation in small lung adenocarcinoma with bronchioloalveolar carcinoma components. Lung Cancer 2009; 65 :328-32.Kubo T, Yamamoto H, Ichimura K, Jida M, Hayashi T, Otani H, Tsukuda K, Sano Y, Kiura K, Toyooka S: DNA methylation in small lung adenocarcinoma with bronchioloalveolar ...
[10] Zhang C, Yu W, Wang L, et al. DNA Methylation Analysis of the SHOX2 and RASSF1A Panel in Bronchoalveolar Lavage Fluid for Lung Cancer Diagnosis[J]. Journal of Cancer, 2017, 8(17):3585-3591. [11] 张毅敏, 王明丽, 吴杰,等. 肺泡灌洗液中SHOX2和RASSF1A基因甲基化联合检测对肺癌的...