This study aims to investigate whether LSD1 mediates the effect of early nerve cell autophagy on apoptosis after spinal cord injury (SCI), in order to provide new ideas for the treatment of neurological damage. Using a rat model of SCI, a combination of behavioral tests, immunohistochemistry, ...
Effects of Hallucinogenic Drugs on the Mind & Body from Chapter 6 / Lesson 3 74K Hallucinogenic drugs are known for their ~'psychedelic~' effects on the mind and body. Explore what hallucinogenic drugs are, how they affect different parts and chemicals of the brain, and how they affect ...
In non-nerve cells, BHC80 can participate in the transcriptional repression of nerve-specific genes and change the transcriptional state of the target genes promoter from activation to repression63. HMG box-containing protein 20B is a member of the high-mobility group which is associated with ...
Given the profound effects of Rcor2 on cortical development, we examined the proliferation and neurogenesis capacities of NSCs/NPCs on Rcor2 depletion during cortical development. Compared with the control group, decreased expressions of NPC markers Sox2 and Nestin were observed by immunostaining in ...
Monitoring the kinetics of cell death induction showed that GSK690 significantly increased JNJ-26481585-induced cell death in a time-dependent manner (Figure 1c). Control experiments confirmed that LSD1 and HDAC inhibitors caused their typical target-specific effects on histone-modifying enzymes, that...