LGI was defined as a C-reactive protein level between 3 and 10 mg/L. Infections were identified by ICD-10 codes in the Danish National Patient Register and ATC-codes in the Danish Prescription Register. Multivariable Cox proportional hazard analysis was used as the statistical model. During 53...
11 This receptor, in turn, binds to DNA and affects the production of messenger RNA, which modifies protein synthesis by the cell.11 The androgen receptor has a polymorphic CAG microsatellite coding for a variable length of glutamine residues, and men with shorter sequences of CAG repeats who ...
Previously, we identified that overexpression of thyroid hormone-responsive protein (THRSP), a gene highly responsive to TH status, induced inattention in male mice. Herein, we sought to explore whether TH function in THRSP-overexpressing (THRSP OE) mice influences ADHD-like (inattention) behavior....
We have found that in early and prodromal Alzheimer patients raised plasma levels of NfL protein, a marker of axonal neurodegeneration, are inversely correlated with raised levels of PK11195 binding, a marker of microglial activation / neuroinflammation, in cortical areas. As raised plasma NfL reflec...
Functional analysis of genetic variation in catechol-O- methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. Am J Hum Genet 75: 807–821. Cohen SM, Nadler JV (1997a). Proline-induced potentiation of glutamate transmission. Brain Res 761: 271–...
In experiments at cell level, low dose radiation induces significant and non-linear effects on micronuclei, chromosome rearrangements and instability, point mutations, and changes in cell cycle protein levels. Studies reviewed by Mothersill and Seymour [5] show low doses have large effects on cells...
ICD: International Statistical Classification of Diseases and Related Health Problems IL: Iinterleukin LBP: Liposaccharide-binding protein PHQ-8: 8-Item Patient Health Questionnaire QALYs: Quality-adjusted life years RCT: Randomised controlled trial RUQ: Resource Use Questionnaire R4DQ: The Rom...
Association between serum C-reactive protein and DSM-IV generalized anxiety disorder in adolescence: findings from the ALSPAC cohort. Neurobiol Stress. 2016;4:55–61. Article PubMed PubMed Central Google Scholar Roifman I, Beck PL, Anderson TJ, Eisenberg MJ, Genest J. Chronic inflammatory ...
In vitro cell samples or in vivo tumor tissues harvested on indicated days were lysed using the radioimmunoprecipitation assay (RIPA) buffer in the presence of protease and phosphatase inhibitor cocktail. The protein concentration was quantified using Pierce BCA protein kit (Thermo Fisher Scientific)....
and diabetes mellitus (DM) (treatment with antidiabetic drug or fasting glucose level ≥126 mg/dL). Definition of incident dementia Incident dementia and prescription of anti-dementia medication at the same time was considered a diagnosis of dementia (ICD-10 codes F00, G30, F01, F02, F03...