A low-protein, high-carbohydrate (LPHC) diet for 15days increased the lipid content in the carcass and adipose tissues of rats. The aim of this work was to investigate the mechanisms of this lipid increase in the retroperitoneal white adipose tissue (RWAT) of these animals. The LPHC diet ...
We have found that in early and prodromal Alzheimer patients raised plasma levels of NfL protein, a marker of axonal neurodegeneration, are inversely correlated with raised levels of PK11195 binding, a marker of microglial activation / neuroinflammation, in cortical areas. As raised plasma NfL reflec...
With the respect to the impact of other factors on dementia, we categorized the study subjects according to their ages, sex, lifestyle (smoking, drinking, and exercise), and metabolic status (diabetes, hypertension and dyslipidemia), and analyzed the hazard ratio after controlling confounding factor...
G. et al. Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure. Science 314, 1930–1933 (2006). CAS PubMed Google Scholar Nackley, A. G. et al. Catechol-O-methyltransferase inhibition increases pain sensitivity through activation of both ...
mice suggest reduced MTAP activity, which is an essential enzyme that controls the salvage synthesis of adenine from the substrate methylthioadenosine.53,54,55As this pathway plays an important role in cellular energy homeostasis and DNA and protein synthesis,56the impaired purine metabolism pathway ...
Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis. Proc Natl Acad Sci U S A. 2015;112(29):9046-9051.PubMedGoogle ScholarCrossref 86. Spirito P. The dawn of a better day for patients with hypertrophic cardiomyopathy. J Am Coll Cardiol. 2015;65(18):1929-1930.Pub...
socioeconomic status CRP C-reactive protein PCA principal component analysis IQR interquartile WBC white blood cell NLR neutrophil-to-lymphocyte ratio PLR platelet-to-lymphocyte ratio 1. Introduction Over the last decade, increasing evidence has emerged suggesting a connection between diet and mental hea...
ICD: International Statistical Classification of Diseases and Related Health Problems IL: Iinterleukin LBP: Liposaccharide-binding protein PHQ-8: 8-Item Patient Health Questionnaire QALYs: Quality-adjusted life years RCT: Randomised controlled trial RUQ: Resource Use Questionnaire R4DQ: The Rom...
Previously, we identified that overexpression of thyroid hormone-responsive protein (THRSP), a gene highly responsive to TH status, induced inattention in male mice. Herein, we sought to explore whether TH function in THRSP-overexpressing (THRSP OE) mice influences ADHD-like (inattention) behavior....
G. et al. Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure. Science 314, 1930–1933 (2006). CAS PubMed Google Scholar Nackley, A. G. et al. Catechol-O-methyltransferase inhibition increases pain sensitivity through activation of both ...