We have found that in early and prodromal Alzheimer patients raised plasma levels of NfL protein, a marker of axonal neurodegeneration, are inversely correlated with raised levels of PK11195 binding, a marker of microglial activation / neuroinflammation, in cortical areas. As raised plasma NfL reflec...
11 This receptor, in turn, binds to DNA and affects the production of messenger RNA, which modifies protein synthesis by the cell.11 The androgen receptor has a polymorphic CAG microsatellite coding for a variable length of glutamine residues, and men with shorter sequences of CAG repeats who ...
We included 15,754 healthy participants from the Danish Blood Donor Study, who completed a questionnaire on health-related items. LGI was defined as a C-reactive protein level between 3 and 10 mg/L. Infections were identified by ICD-10 codes in the Danish National Patient Register and ATC-...
P844 SHORT-TERM EFFECT OF LOW-CALORIE DIET (LCD) VERSUS ISOCALORIE DIET (ICD) ON BLOOD AMINOTRANSFERASES LEVEL AND LIPIDS PROFILE IN PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS (NASH) - Journal of Hepatologydoi:10.1016/S0168-8278(14)61005-9Selezneva, K....
32 D, Flow diagram summarizing outcome of ICD therapy for 224 children and adolescents (<20 years of age).33 ACC/AHA indicates American College of Cardiology/American Heart Association; BP, blood pressure; CAD, coronary artery disease; EF, ejection fraction; LV, left ventricular; LGE, late ...
Beta-casein is a major protein in cow’s milk, of which A1 and A2 are the most frequent variants. Recent evidence implicates A1 beta-casein consumption in mechanisms that are of potential importance to mental health, yet its possible effects on psycholog
Functional analysis of genetic variation in catechol-O- methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. Am J Hum Genet 75: 807–821. Cohen SM, Nadler JV (1997a). Proline-induced potentiation of glutamate transmission. Brain Res 761: 271–...
CD271 protein is expressed rarely in a tumor bulk20,25 and consequently only few human melanoma cell lines derived from tumors express high levels of the protein, as revealed by Western blot analysis (Supplementary Fig. 1a). To assess the growth of cells with different CD271 levels, we ...
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder, potentially with a biological basis; however, its exact cause remains unknown. Thyroid hormone (TH) abnormalities are more prevalent in patients with ADHD than in the gener
Fig. 5: Ultrasound responsive chemotherapeutics potently inhibited tumor growth in vivo and induced strong antitumor immunity. aC57BL/6 mice were intravenously injected with indicated formulations and the blood samples were collected at indicated time points and imaged by the IVIS optical imaging system...