AimDiffuse low-grade glioma (LGG) patients have a tendency to develop glioblastoma multiforme within 5–10 years, with only 15 months life expectancy. The present study aimed to decode a diagnostic and prognostic gene signature in LGG and identify repositioned potential candidate biomarker ...
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Additionally, the uncertainty regarding their life expectancy led to difficulties in making decisions about the future. They also perceived a lack of control over their future and the time they had left. CONCLUSIONS. LGG have a significant impact on AYA patients. However, this impact is not ...
daily life challengeslow grade gliomaBACKGROUND. Low-grade gliomas (LGG) are among the most frequently occurring tumors in adolescent and young adult (AYA) patients (aged 18鈥 39 years old at primary diagnosis). These tumors have a variable prognosis, presenting challenges for patients in shaping...
Objective:For a long time, return to work (RTW) has been neglected in patients harboring a diffuse low-grade glioma (LGG). However, a majority of LGG patients worked at time of diagnosis. Moreover, these patients now live longer given current treatment paradigms, especially thanks to early ...
GliomaIntraoperative magnetic resonance imagingNeuroimagingIntroductionThe treatment of low-grade gliomas (LGGs) in pediatric age is still controversial. However, most authors report longer life expectancy in case of completely removed cerebral gliomas. Intraoperative magnetic resonance imaging (iMRI) is ...
GliomaChildrenNeuroimagingIntraoperative magnetic resonance imagingThe treatment of low-grade gliomas (LGGs) in pediatric age is still controversial. However, most authors report longer life expectancy in case of completely removed cerebral gliomas. Intraoperative magnetic resonance imaging (iMRI) is ...
Low-grade gliomaQuality of lifeSocioeconomicsLow-grade glioma (LGG) usually occurs in young patients who enjoy an active familial and socio-professional life. Because awake surgery in LGG patients has resulted in a significant improvement of both functional and oncological outcomes, and because the ...
Patients suffering from diffuse Low-Grade Glioma (LGG) are usually young adults and present long life expectancy thanks to multimodal therapeutic management. In this context, the preservation of quality of life (QoL) is essential, and sexual health is part of it. We reviewed here the current kn...
Of relevance to glioma, statins target CD36, a scavenger receptor that is highly expressed in pilocytic astrocytoma [21]. Fluvastatin also showed an inhibitory and cytotoxic effect on several high-grade glioma cell lines [18,22,23]. Celecoxib is a cyclooxygenase 2 (COX-2) inhibitor and has ...