Low grade gliomaastrocytomaoligoastrocytomaoligodendroglioma1p/19qisocitrate dehydrogenase (IDHradiationchemotherapyprognosisSummary Low grade gliomas (LGG) are slow-growing brain tumors that typically affect young adults. While treatable with surgery, radiation, and chemotherapy, LGG are not curable and carry...
Low-Grade Gl i omas i n Adul ts ×÷ÕߣºJeanine T. Grier, Tracy Batchelor ¡ ¾¹Ø¼ü´Ê¡ ¿ Low-grade, glioma Key Words. Low-grade glioma ; Astrocytoma ; Oligodendroglioma ABSTRACT Low-grade gliomas are a heterogeneous group of neoplasms usually encountered in...
13. Scholars have revealed the inhibitory effect of PANoptosis on tumor growth in diverse cancer lineages, shedding more light on the investigation of biomarkers and therapeutic targets for patients14. However, the specific roles of PANoptosis in glioma prognosis remain...
low-grade glioma. In doing so we discuss the specific molecular drivers of pediatric low grade glioma and how to effectively test for them, review the newest therapeutic agents and their utility in treating this disease, and propose a risk-based stratification system that considers both clinical a...
Lower-grade gliomas (LGGs) exhibit highly variable clinical behaviors, while classic histology characteristics cannot accurately reflect the authentic biological behaviors, clinical outcomes, and prognosis of LGGs. In this study, we carried out analyses of whole exome sequencing, RNA sequencing and DNA...
grade gliomas, they may demonstrate extremely aggressive growth and progression. Recent studies have helped delineate genetic markers that correlate with low grade glioma clinical behavior. These markers, both alone and in combination, offer the possibility of more accurate prognostication than ...
Fatty acid metabolism disruptions affect low-grade gliomas (LGGs), with glioma cells depending on fatty acids for survival. Targeting fatty acid oxidation through the acyl-coenzyme A synthetase long-chain (ACSL) family could alleviate glioma growth and improve prognosis management. However, the integr...
and tumors of mixed neuronal-glial morphology. These tumors are considered grades I and II according to the current WHO classification where they are distinguished from high grade glioma on the basis of specific morphologic features or, in the case of diffuse glioma, based on the absence of necr...
To report the long-term follow-up of a cohort of adult patients with LGG post-operatively irradiated in one institution, and to identify prognostic factors for progression free survival. Background There is little consensus about the optimal treatment for low-grade glioma (LGG), and the clinical...
Glioneuronal tumors are somewhat related given that a low-grade glioma component is frequent and they are also characterized by similar demographics. The prognosis for these tumors is generally good, but complete surgical resection may not be possible in specific locations, therefore they have a ...