Low dose tamoxifen in the treatment of metastatic breast cancer at the pennsylvania hospital - International Journal of Radiation Oncology Biology Physicsdoi:10.1016/0360-3016(77)90380-7Harvey LernerM.Catherine GodwinElsevier Inc.International Journal of Radiation Oncology Biology Physics...
On the basis of these results, the authors concluded that low-dose tamoxifen retains its ability to suppress breast cell proliferation but has diminished activity in modulat- ing serum biomarkers. The authors also conclude that the risk- to-benefit ratio associated with tamoxifen may be improved ...
The Benefit-Harm Charts show that a substantial proportion of the population is likely to benefit from low dose aspirin for primary prevention of cardiovascular disease and cancer. For example, a large proportion of the general population has a low 10-year risk (<3 %) for severe GI bleeds [...
4801 An enhancement of breast cancer risk reduction by tamoxifen (T) was observed in hormone replacement therapy users in the Italian tamoxifen trial. Based on this observation we conducted a ranging low dose tamoxifen randomised phase II trial in healthy postmenopausal women. Our goal is to reach...
PATIENT(S):A 30-year-old male. INTERVENTION(S):Clomiphene citrate, 100-mg challenge for 5 days, followed by treatment at same dose for 2 months. MAIN OUTCOME MEASURE(S): Clinical symptoms, androgen decline in aging male questionnaire, total T, FSH, LH. ...
Vol.:(0123456789) 1 3Breast Cancer Research and Treatment (2022) 193:417–427 https://doi.org/10.1007/s10549-022-06577-5CLINICAL TRIALInitiation and tolerance of chemoprevention among women with high‑risk breast lesions: the potential of low‑dose tamoxifenBrittany Bychkovsky 1,2,3 · Alis...
Effect of low-dose tamoxifen on IGF-I/IGFBP-3 and estradiol/SHBG ratio and their prognostic/predictive effect in DCIS/LCIS/ADH.doi:10.1200/JCO.2024.42.16_suppl.1051021110510#Background:Babytam (BT), 5 mg/day for 3 years (y) is a popular choice for preventive therapy after breast DCIS...
A study protocol is presented based on the assessment of the effect of different interventions such as tamoxifen at 10 mg every other day (LDT), intermittent caloric restriction (ICR) two days per week, lifestyle intervention (LI, step counter use) and their combina...
Two-way ANOVA tests also demonstrated significant interactions between tamoxifen treatment and gender on the expression of thermogenic markers in adipose tissues.Tamoxifen, even at a low dose, remarkably increases thermogenesis in adipose tissues of female mice; meanwhile, such a low dose could be ...
The objective of this study was to evaluate the use of low dose tamoxifen at our institution and determine how many patients preferred this option. Methods: We performed a retrospective chart review of women who were diagnosed with DCIS, LCIS, ADH, and/or ALH at our institution from January ...