Spirometry, lung volume, and carbon monoxide diffusing capacity using the single-breath method (DLCO) were measured with a Chestac-65 V (Chest MI Corp., Tokyo, Japan). CT acquisition All CT images at full inspiration were obtained with an Aquilion 64 scanner (Toshiba; Tokyo, Japan). The CT...
As DLCO is a mathematical product of alveolar carbon monoxide uptake efficiency and alveolar volume, impairments may be due to either one or both of these parameters [50]. Limitations in alveolar carbon monoxide uptake efficiency may be explained by COVID-19-induced alveolar capillary damage, micro...