Methods: Data from the Australian IPF Registry included demographic features, comorbidities, St George Respiratory Questionnaire (SGRQ), Hospital Anxiety & Depression (HAD-A & D) scale, UCSD Shortness of BreathQuestionnaire (UCSD), cough, oxygen use, spirometry, DLCO & 6MWT parameters. Linear ...
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When comparing cyclophosphamide with mycophenolate mofetil (MMF) at 1 year (two trials, 149 participants), there was no significant difference in lung function (p=0.61) or diffusion capacity (p=0.76). Improvement in lung function was more pronounced in patients with worse baseline spirometry and...
Previous spirometry testing demonstrated preserved lung volumes, forced expiratory volumes and vital capacity. DLCO (lung diffusion capacity for carbon monoxide) was at the lower limit of normal. A ventilation-perfusion scan excluded pulmonary emboli. Cardiopulmonary exercise testing demonstrated good ...